PedAM
Pediatric Disease Annotations & Medicines
| Disease | leukemia |
| Phenotype | C0026985|myelodysplasia |
| Sentences | 32 |
| PubMedID- 25975285 | On multivariable analysis, neither acute myeloid leukemia with myelodysplasia-related changes nor acute myeloid leukemia-not evaluable showed significantly different event-free survival compared with acute myeloid leukemia-not otherwise specified in the 137 patients treated with induction chemotherapy. |
| PubMedID- 25379617 | Faggot-like cells observed in acute myeloid leukemia with myelodysplasia-related changes mimicking acute promyelocytic leukemia. |
| PubMedID- 22911588 | To the best of our knowledge, this is the first report of acute myeloid leukemia with myelodysplasia-related changes with i(17q) after the use of a hypomethylating agent. |
| PubMedID- 20552819 | In the past five years 3 patients with primary lymphedema have been diagnosed with myelodysplasia (leading to acute leukemia) or acute leukemia. |
| PubMedID- 26084204 | Recent studies have shown that acute myeloid leukemia with myelodysplasia-related changes (aml-mrc) exhibits a worse clinical outcome than aml not otherwise specified (aml-nos). |
| PubMedID- 21102413 | Following the current world health organization classification algorithm, these cases were classified as: 13 acute myeloid leukemia with myelodysplasia-related changes, 3 therapy-related acute myeloid leukemia, and 1 chronic myelogenous leukemia blast crisis, and one unclassifiable due to insufficient clinical information. |
| PubMedID- 26071460 | Objectives: acute myeloid leukemia with myelodysplasia-related changes (aml-mrc) is a heterogeneous disorder defined by morphologic, genetic, or clinical features. |
| PubMedID- 21768886 | We report a unique pediatric case of hypergranular acute myeloid leukemia with myelodysplasia-related changes. |
| PubMedID- 26071461 | Most cases of amkl in adults would be classified as acute myeloid leukemia with myelodysplasia-related changes according to the who classification, but this approach deemphasizes their unique clinical, morphologic, and immunophenotypic features. |
| PubMedID- 22950073 | Detection of runx1-mecom fusion gene and t(3;21) in a very elderly patient having acute myeloid leukemia with myelodysplasia-related changes. |
| PubMedID- 20954271 | Acute myeloid leukemia with myelodysplasia-related changes with erythroid differentiation involving pleural fluid: a case report and brief cytopathologic review. |
| PubMedID- 22022200 | For example, we were able to identify a very rare npm1-mlf1 rearrangement from an acute myeloid leukemia with myelodysplasia-related changes (aml-mrc) patient who accompanied a complex karyotype by utilizing the multiplex rt-pcr testing method (2). |
| PubMedID- 24824767 | Acute myeloid leukemia (aml) with myelodysplasia-related changes is characterized by the presence of multilineage dysplasia (mld), frequently related to high-risk cytogenetics and poor outcome. |
| PubMedID- 25669040 | Four cases were presented and discussed mainly from the viewpoint of cellular morphology: two cases of acute myeloid leukemia (aml) with myelodysplasia-related changes, one case of adult t-cell leukemia/lymphoma, and one case of chronic myelogenous leukemia in the blast phase. |
| PubMedID- 21447369 | Impaired mitochondrial gene transcription in myelodysplastic syndromes and acute myeloid leukemia with myelodysplasia-related changes. |
| PubMedID- 26239249 | Mds: myelodysplastic syndrome, aml-mrc: acute myeloid leukemia with myelodysplasia related changes, ptd: partial tandem duplication, cn-aml: cytogenetically normal acute myeloid leukemia. |
| PubMedID- 25148222 | Depletion of stat5 blocks tel-syk-induced apmf-type leukemia with myelofibrosis and myelodysplasia in mice. |
| PubMedID- 20603581 | [clinical importance of morphological multilineage dysplasia in acute myeloid leukemia with myelodysplasia related changes]. |
| PubMedID- 24852219 | Peripheral blood features of acute myeloid leukemia with myelodysplasia-related changes developing in a patient with sickle cell anemia. |
| PubMedID- 22186000 | Acute myeloid leukemia with myelodysplasia-related changes mimicking acute promyelocytic leukemia. |
| PubMedID- 25860933 | In the who 2008 classification, acute myeloid leukemia (aml) with myelodysplasia-related changes (aml-mrc) is defined as a distinct entity by the presence of multilineage dysplasia (mld), and/or myelodysplastic syndrome (mds)-related cytogenetics, and/or previously diagnosed mds or mds/myeloproliferative neoplasm (mds/mpn) [1]. |
| PubMedID- 25199050 | Myelodysplastic syndromes (mds) are a group of clonal hematopoietic stem cell diseases, which eventually result in leukemic transformation (acute myelogenous leukemia with myelodysplasia-related changes, aml-mrc). |
| PubMedID- 20980053 | Novel variant form of t(11;22)(q23;q13)/mll-ep300 fusion transcript in the evolution of an acute myeloid leukemia with myelodysplasia-related changes. |
| PubMedID- 24861848 | Characteristics of acute myeloid leukemia with myelodysplasia-related changes: a retrospective analysis in a cohort of chinese patients. |
| PubMedID- 26071459 | Results: we explored prognostic implications of gene mutations such as dnmt3a, issues related to the classification of aml cases with the npm1 mutation, and myelodysplasia-related changes arising from chronic myelomonocytic leukemia after a short latency interval. |
| PubMedID- 23874874 | Single missense mutations within the runt domain severely diminish or even ablate binding runx1 dna binding and are associated with myelodysplasia and the development of acute myeloid leukemia, perhaps by haploinsufficiency and lowered gene dosage or by interference with the homodimerization of wildtype runx1 or its binding to cbfβ. |
| PubMedID- 24695467 | Granulocyte, monocyte and blast immunophenotype abnormalities in acute myeloid leukemia with myelodysplasia-related changes. |
| PubMedID- 22535592 | Acute myeloid leukemia with myelodysplasia-related changes are characterized by a specific molecular pattern with high frequency of asxl1 mutations. |
| PubMedID- 24661537 | Temporomandibular joint arthritis as an initial presentation of acute myeloid leukemia with myelodysplasia-related changes: a report of an unusual case. |
| PubMedID- 24941894 | Acute myeloid leukemia with myelodysplasia-related changes showing basophilic differentiation. |
| PubMedID- 24716233 | Giant multilobated mastocytes(promastocytes) in the setting of a refractory acute myeloid leukemia with myelodysplasia-related changes and monosomal karyotype. |
| PubMedID- 23888241 | The third possibility is that, according to the who classification of tumors of hematopoietic and lymphoid tissues, our patient could have been classified as acute myelogenous leukemia (aml) with myelodysplasia-related changes.7 although this specific category excludes cases characterized by genetic abnormalities of aml accompanied by recurrent abnormalities such as t(15;17), our case might be classified in this category. |
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