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PedAM

Pediatric Disease Annotations & Medicines




Disease leishmaniasis
Phenotype C0023283|cutaneous leishmaniasis
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PubMedID- 22566961 Protective immunity against visceral leishmaniasis, as with species causing cutaneous leishmaniasis, is dependent on an il-12 driven type-1 response and ifn-γ production (murray, 1997; engwerda et al., 1998), which results in the induction of parasite killing by macrophages primarily via the production of reactive nitrogen and oxygen intermediates (murray and nathan, 1999).

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