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PedAM

Pediatric Disease Annotations & Medicines




Disease lactic acidosis
Phenotype C0035078|renal failure
Sentences 5
PubMedID- 26290421 However, metformin can very rarely lead to lactic acidosis in patients with renal failure.
PubMedID- 23341794 We diagnosed intestinal discomfort and lactic acidosis metformin associated with acute renal failure secondary to dehydration.
PubMedID- 24160916 The lower use could be due to the reluctance of physicians to prescribe to the elderly due to the side effects related to metformin (gastrointestinal upset, including diarrhea, nausea, vomiting and flatulence) and the rare possibility of lactic acidosis in those with renal failure [37].
PubMedID- 21853087 Thus, as reported in this case series of metformin-treated patients, severe lactic acidosis associated with acute renal failure and/or other sepsis-like symptoms should systematically lead physicians to request metformin assays.
PubMedID- 21467829 However, in the majority of cases, lactic acidosis is diagnosed in patients with severe acute renal failure, which itself can cause lactic acidosis.

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