PedAM
Pediatric Disease Annotations & Medicines
| Disease | ischemia |
| Phenotype | C1527311|brain edema |
| Sentences | 4 |
| PubMedID- 24312074 | Traumatic brain injury leads to progressive pathophysiological changes resulting in a reduction in cerebral blood flow and a decrease in tissue oxygen levels leading to ischemia, bbb disruption with brain edema (100). |
| PubMedID- 20924629 | Pretreatment with tgn-020 significantly reduced brain edema associated with brain ischemia, as reflected by percentage of brain swelling volume (%bsv), 12.1 +/- 6.3% in the treated group, compared to (20.8 +/- 5.9%) in the control group (p < 0.05), and in the size of cortical infarction as reflected by the percentage of hemispheric lesion volume (%hlv), 20.0 +/- 7.6% in the treated group, compared to 30.0 +/- 9.1% in the control group (p < 0.05). |
| PubMedID- 26413530 | Furthermore, ischemia is a cause of brain edema surrounding the hematoma region [34, 35]. |
| PubMedID- 25100404 | The neurological severity score was improved and both ischemia-induced brain edema and bbb leakage were reduced in msc-treated mice. |
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