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PedAM

Pediatric Disease Annotations & Medicines




Disease ischemia
Phenotype C0178664|glomerulosclerosis
Sentences 2
PubMedID- 23850447 Results: a similar pattern was seen in all 8 biopsy specimens, with extensive glomerulosclerosis (29%-78%) and signs of chronic glomerular ischemia in combination with tubular atrophy and interstitial fibrosis, but only mild vascular lesions.
PubMedID- 23939543 In vivo, rats rendered hyperuricemic by means of a uricase inhibitor develop an afferent arteriolopathy that decreases luminal diameter and produces renal ischemia, leading to glomerulosclerosis and tubulointerstitial fibrosis (23).

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