PedAM
Pediatric Disease Annotations & Medicines
| Disease | ischemia |
| Phenotype | C0034735|raynaud\'s phenomenon |
| Sentences | 2 |
| PubMedID- 21050433 | Ssc vasculopathy mainly affects small arteries, causing reduced blood flow and tissue ischemia, which leads to raynaud's phenomenon, digital ulcers, and gangrene [1]. |
| PubMedID- 20842555 | More expensive second-line agents, such as phosphodiesterase-5 inhibitors, endothelin receptor antagonists, and intravenous prostanoids, are reserved for refractory cases of secondary raynaud's phenomenon with severe digital ischemia leading to ulceration or gangrene. |
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