PedAM
Pediatric Disease Annotations & Medicines
| Disease | ischemia |
| Phenotype | C0011847|diabetes |
| Sentences | 33 |
| PubMedID- 24125539 | In this study, we demonstrate that galbudab produced both glucose-lowering and cardioprotective effects, suggesting that galbudab may have potential both to manage hyperglycemia and to limit myocardial ischemia injury in patients with diabetes mellitus who are at high risk for coronary artery disease and acute coronary syndrome. |
| PubMedID- 20929989 | Alfediam/sfc high-risk criteria: the alfediam recommended screening for inducible myocardial ischemia in patients with type 2 diabetes (8) with one of the following: age >60 years; duration of diabetes >10 years and at least two other cardiovascular risk factors; peripheral arterial disease; and proteinuria and microalbuminuria with at least two other cardiovascular risk factors. |
| PubMedID- 20484135 | Plerixafor represents a potential therapeutic agent for improving ischemia-mediated pathology associated with diabetes by reducing bone marrow sdf-1alpha, restoring normal pc mobilization and tissue healing. |
| PubMedID- 25849290 | Indeed, the angiogenic response after ischemia is attenuated in patients with diabetes, interfering with the response to treatment [16,17]. |
| PubMedID- 23393213 | Because silent ischemia commonly occurs in patients with diabetes mellitus, biochemical detection of subclinical myocardial necrosis may occur without overt clinical presentation (18) and may portend further disease progression (19). |
| PubMedID- 26230411 | These data suggest that peripheral ischemia in diabetes is accompanied with reduced pge2. |
| PubMedID- 24843408 | Myocardial ischemia in patients with diabetes is often asymptomatic and frequently in an advanced stage when it becomes clinically manifest. |
| PubMedID- 20692245 | Insertion/insertion genotype of alpha(2b)-adrenergic receptor gene polymorphism is associated with silent myocardial ischemia in patients with type 2 diabetes mellitus. |
| PubMedID- 20215456 | Cardiac autonomic neuropathy (can), which can be documented by abnormal heart rate variability (hrv), occurs commonly in patients with diabetes and is associated with silent myocardial ischemia (4) and increased mortality (5). |
| PubMedID- 24082888 | Moreover, the fact of studying bm-mscs differentiation in the presence of low oxygen concentration may be relevant to understanding the lack of repair processes that occur with severe hypoxia such as in situations of severe vascular ischemia, which occurs in patients with atherosclerosis or diabetes and in patients with inflammatory conditions such as arthritis. |
| PubMedID- 25206883 | In ma's study (2009), the diabetes combined with cerebral ischemia model was established using a double-vessel occlusion and femoral artery bloodletting method, which can lead to hypotension and low brain perfusion in addition to ischemic stress induced by vessel occlusion. |
| PubMedID- 24223835 | This was an intuitively appealing hypothesis given the enhanced damage caused by ischemia in patients with uncontrolled diabetes who lack insulin and are thereby hyperglycemic [32]. |
| PubMedID- 25881261 | Foot ischemia in patients with diabetes may be attributed to atherosclerotic macrovascular disease and additional microcirculatory dysfunction. |
| PubMedID- 23724400 | Normally diabetes is associated with microvascular ischemia of the bone, endothelial cell dysfunction and decreased bone turn over and remodeling as well as induced apoptosis of osteoblasts and osteocytes. |
| PubMedID- 25995614 | The translational significance of this study is to develop a simple combined tool for diagnostics and treatment of acute myocardial ischemia in patients with atherosclerosis or diabetes with impaired bioavailability of no. |
| PubMedID- 23970955 | Co-morbid medical conditions, such as diabetes, that lead to ischemia of ocular tissues appear to be an important factor to consider in patients with this surgery. |
| PubMedID- 25722688 | Thus, the purpose of the present study was to investigate the role of the rage-mapks pathway in diabetes mellitus complicated by focal brain ischemia in rats. |
| PubMedID- 21552382 | [12] presented a 70-year-old man suffering from non-insulin-dependent diabetes complicated by nonocclusive colonic ischemia because of altered mesenteric microcirculation and a hypercoagulable state who was treated conservatively by vasodilator infusion and anticoagulant therapy. |
| PubMedID- 22374638 | This may be explained as follows: initially, retinal arteriolar caliber decreases in response to elevated blood pressure, which in diabetes leads to ischemia and tissue hypoxia due to the limited vasodilatory capacity of the vessels. |
| PubMedID- 22665920 | Outcomes of three years of teamwork on critical limb ischemia in patients with diabetes and foot lesions. |
| PubMedID- 22437482 | Moreover, nbp could reduce the amyloid β peptide generation promoted by diabetes in ischemia by inhibiting over-activated autophagy (32). |
| PubMedID- 23275364 | (21) noted improved postprandial microvascular reactive hyperemia after ischemia in adults with non–insulin-dependent diabetes with 2 g/day of n-3 pufa. |
| PubMedID- 21070849 | Together, these data reveal that dipyridamole therapy is an effective modality for the treatment of chronic tissue ischemia during diabetes and highlights the importance of dipyridamole antioxidant activity in restoring tissue no bioavailability during diabetes. |
| PubMedID- 25964891 | One example is ischemic disease due to arterial obstruction, where an impaired response to ischemia in diabetes or aging is a critical risk factor. |
| PubMedID- 21838881 | The relationship between plasma opg concentrations and signs of myocardial ischemia on mps in patients with type 2 diabetes has previously been investigated by avignon et al. |
| PubMedID- 24330253 | The interaction among all these conditions may determine the overall response of the myocardium to ischemia in patients with diabetes mellitus. |
| PubMedID- 24303086 | Clinical data strongly supports an increased susceptibility to myocardial ischemia-reperfusion injury in patients with diabetes mellitus [4]. |
| PubMedID- 22313801 | However, the effect on angiogenesis in myocardial ischemia with diabetes mellitus (dm) is still unknown. |
| PubMedID- 22291768 | Some of the top 10 optn variables associated with highest percentage increase in los and medicare payments were common to both outcomes and included type i diabetes as cause of esrd, cold ischemia time > 36 h, dcd, dialysis duration longer than 5 years, the presence of dr mismatches, history of myocardial infarction and presence of functional limitations. |
| PubMedID- 20599350 | Critical limb ischemia in patients with diabetes at the organ complication stage represents a considerable challenge in vascular medicine. |
| PubMedID- 21754920 | Besides, regular oral administration of metformin increased myocardial tolerance to ischemia in animals with type i diabetes mellitus (t1dm) [8]. |
| PubMedID- 24640771 | [the effect of metformin on myocardial tolerance to ischemia in rats with diabetes mellitus type 2]. |
| PubMedID- 25945116 | Mitochondria play an essential role in cerebral ischemia with diabetes [46]. |
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