PedAM
Pediatric Disease Annotations & Medicines
| Disease | irritable bowel syndrome |
| Phenotype | C0011991|diarrhea |
| Sentences | 49 |
| PubMedID- 25788484 | Worsened gi symptoms, such as abdominal pain, bloating or diarrhea are observed in patients with irritable bowel syndrome (ibs) during menses. |
| PubMedID- 22415197 | The jejunum of diarrhea-predominant irritable bowel syndrome shows molecular alterations in the tight junction signaling pathway that are associated with mucosal pathobiology and clinical manifestations. |
| PubMedID- 23618477 | Carnosine had 2 potentially beneficial effects: wais-r scores increased significantly, and there was a decrease in diarrhea associated with irritable bowel syndrome. |
| PubMedID- 20230550 | Objectives: the study aims to quantify the maximum acceptable risk (mar) of treatment-related adverse events (aes) that women with diarrhea-predominant irritable bowel syndrome (ibs) are willing to accept in exchange for symptom relief. |
| PubMedID- 20136586 | Alosetron for severe diarrhea-predominant irritable bowel syndrome: safety and efficacy in perspective. |
| PubMedID- 20134008 | Travel and travelers' diarrhea in patients with irritable bowel syndrome. |
| PubMedID- 25046944 | [treating irritable bowel syndrome with diarrhea patients by yigan fupi decoction: a randomized controlled trial]. |
| PubMedID- 25769413 | High prevalence of idiopathic bile acid diarrhea among patients with diarrhea-predominant irritable bowel syndrome based on rome iii criteria. |
| PubMedID- 22937091 | Epidemiology of functional diarrhea and comparison with diarrhea-predominant irritable bowel syndrome: a population-based survey in china. |
| PubMedID- 23346005 | The 5-ht3 receptor antagonist alosetron is useful in the treatment of diarrhea in patients with irritable bowel syndrome, but must be avoided in more severe cases because of the risk of constipation [3]. |
| PubMedID- 21592902 | Background: microscopic colitis (mc) and irritable bowel syndrome with diarrhea (ibsd) have a similar clinical and endoscopic presentation. |
| PubMedID- 24667275 | The crohn’s disease activity index, which is widely used in cd patients, has been proven quite inaccurate in this context (for instance, the score might be raised in the absence of inflammation because of diarrhea and pain due to irritable bowel syndrome or bacterial overgrowth) [10]. |
| PubMedID- 24160947 | Data were also presented on how bile acids can increase susceptibility to diarrhea in patients with irritable bowel syndrome (ibs) and on how the type of food intake can favor the development of symptoms. |
| PubMedID- 25949526 | The clinical potential of ramosetron in the treatment of irritable bowel syndrome with diarrhea (ibs-d). |
| PubMedID- 22936895 | Therefore, further studies are needed to confirm whether pert improves clinical symptoms such as diarrhea in patients with irritable bowel syndrome. |
| PubMedID- 21056283 | We hypothesized that diarrhea-predominant irritable bowel syndrome (d-ibs) patients would exhibit an increase in plasma tryptophan due to alterations in tryptophan metabolism. |
| PubMedID- 24256141 | We investigated the relationship between mast cells and the gut hormones substance p and vasoactive intestinal peptide (vip) in irritable bowel syndrome with diarrhea (ibs-d). |
| PubMedID- 25970536 | Development and validation of a biomarker for diarrhea-predominant irritable bowel syndrome in human subjects. |
| PubMedID- 23915679 | Direct consequences are obstipation or diarrhea as opposite aspects of the irritable bowel syndrome, and more indirectly, alteration of appetite, feeling of fullness, flatulence, bloatedness, and eventually leading to altered absorption of nutrients. |
| PubMedID- 23667756 | Methods: rectal biopsies from 16 patients with diarrhea-predominant irritable bowel syndrome (ibs-d) and 7 normal subjects were assessed for tryptase activity and macromolecular permeability using horseradish peroxidase in ussing chambers. |
| PubMedID- 21442822 | [forty cases of irritable bowel syndrome in diarrhea type treated with dog days moxibustion]. |
| PubMedID- 23583433 | Background & aims: simultaneous agonism of the mu-opioid receptor and antagonism of the delta-opioid receptor can reduce abdominal pain and diarrhea in patients with irritable bowel syndrome with diarrhea (ibs-d) without constipating side effects. |
| PubMedID- 26140004 | Methods: irritable bowel syndrome patients with diarrhea (ibs-d) and healthy volunteers (hvs) were enrolled and received a 10 g, 20 g, or 40 g dose lactose hydrogen breath test (lhbt) in a randomized, double-blinded, controlled trial. |
| PubMedID- 23097866 | Based on these findings, current recommendations suggest that no extra diagnostic tests have to be performed in those patients, apart from the serological tests in search of celiac disease, which are recommended for patients presenting an irritable bowel syndrome with diarrhea or a mixed-type irritable bowel syndrome. |
| PubMedID- 24322196 | The following diagnosis were established: irritable bowel syndrome with diarrhea in 16, functional abdominal pain in 8, short stature in 10, lactose intolerance in 3, celiac disease in 1, food allergy in 1 and giardiasis in 1 patient. |
| PubMedID- 23595519 | Background: both ulcerative colitis (uc) and diarrhea-predominant irritable bowel syndrome (ibs-d) are associated with alterations in enteric serotonin (5-ht) signaling. |
| PubMedID- 22444104 | Conclusion: in irritable bowel syndrome with diarrhea, tricyclic antidepressants and alosetron are associated with a significant number needed to harm compared with rifaximin. |
| PubMedID- 25323816 | A 36-year-old male who carried a diagnosis of irritable bowel syndrome presented with chronic watery diarrhea and was found to have hepatomegaly on physical exam. |
| PubMedID- 24040053 | Specifically, acute stressors and crf injected into the brain or the periphery induces a rapid onset stimulation of colonic motor function in rodents, a response that is largely mediated by activating crf1 receptors in both the brain and the colon and reproducing symptoms of irritable bowel syndrome (ibs) with diarrhea (ibs-d) [8], [9]. |
| PubMedID- 26026602 | Sbi is predominantly igg (> 50 %) and intended for oral consumption to provide distinctive nutritional requirements for the clinical dietary management of specific gi conditions under physician supervision (e.g., in irritable bowel syndrome with diarrhea (ibs-d), ibd, and hiv-associated enteropathy) [18]. |
| PubMedID- 24843956 | [thirty two cases of diarrhea-predominant irritable bowel syndrome treated by ginger-partitioned moxibustion and acupoint application in dog days]. |
| PubMedID- 24251699 | Dietary fodmaps have been shown to reduce gastrointestinal symptoms, including diarrhea, in those with irritable bowel syndrome and, given a high-enough dose, will induce a laxative effect in most people. |
| PubMedID- 26533536 | Translatability assessment and linguistic validation of the patient-reported outcome instrument for irritable bowel syndrome with diarrhea (ibs-d pro). |
| PubMedID- 21805417 | Postprandial platelet-poor plasma 5-hydroxytryptamine concentrations during diarrhea and constipation periods of alternatingtype irritable bowel syndrome patients. |
| PubMedID- 20303355 | Serotonin signaling is altered in irritable bowel syndrome with diarrhea but not in functional dyspepsia in pediatric age patients. |
| PubMedID- 22679908 | Background: tricyclic antidepressants have good efficacy in irritable bowel syndrome with diarrhea (ibs-d), but their clinical use is limited by considerations of tolerability. |
| PubMedID- 23862208 | I have chronic diarrhea because of irritable bowel syndrome (ibs). |
| PubMedID- 25930081 | The mucosal gene expression in rectosigmoid mucosa (rsm) in irritable bowel syndrome with diarrhea (ibs-d) is unknown. |
| PubMedID- 23393411 | Thirty children who presented from 1992 to 1999 with chronic or intermittent diarrhea (functional disorder of bowel, irritable bowel syndrome [ibs], in infancy chronic non-specific diarrhea) were recruited, examined, treated, and reexamined after 50 days, similar to a protocol reported previously.7 diarrhea was defined as the daily emission of more than 5 grams of feces per kg of body weight under a usual western diet – ie, with 0.6 ± 0.4 g of fiber/d/kg.16 children with histories of either chronic (minimum of 2 months) or intermittent diarrhea (ill with diarrhea for at least 15 of the preceding 90 days) were enrolled. |
| PubMedID- 24257177 | [association between diarrhea-predominant irritable bowel syndrome and htr3a, htr3e gene polymorphism in yangzhou,jiangsu province, china]. |
| PubMedID- 25091249 | Comments on "the jejunum of diarrhea-predominant irritable bowel syndrome shows molecular alterations in the tight junction signaling pathway that are associated with mucosal pathobiology and clinical manifestations". |
| PubMedID- 26130631 | Background/aims: there are limited therapeutic options available for irritable bowel syndrome with diarrhea (ibs-d). |
| PubMedID- 25664061 | Methods: serum cytokines of ulcerative colitis and irritable bowel syndrome with diarrhea patients including il-6, il-10, il-13, il-17, tnf-alpha and tgf-beta were analyzed by enzyme linked immunosorbent assay, and ulcerative colitis activity were assessed by mayo scoring system. |
| PubMedID- 23006460 | Among the diseases causing chronic diarrhea, diagnosis of irritable bowel syndrome (ibs) is controversial and is based on the patient's symptoms and exclusion of other diseases. |
| PubMedID- 20832178 | diarrhea predominant irritable bowel syndrome ibs (ibs-d) and functional diarrhea constitute 50% of cases treated by gastroenterology specialists and a significant proportion of those treated in a primary physicians practice. |
| PubMedID- 21537540 | Methods: based on rome iii criteria, 61 irritable bowel syndrome with diarrhea patients (18 years old or more) were included in the evaluation. |
| PubMedID- 23984599 | In irritable bowel syndrome both forms with diarrhea (13) and with constipation (13) were observed. |
| PubMedID- 25674029 | Recent studies in humans demonstrate that sbi is safe and improves gastrointestinal symptoms (eg, chronic loose and frequent stools, abdominal discomfort, bloating, urgency) in irritable bowel syndrome with diarrhea (ibs-d)17 and hiv-associated enteropathy.18 approximately 25–50% of orally administered igg survives digestion in the stomach and small intestine. |
| PubMedID- 25880525 | More recent studies have also shown efficacy of oral serum-derived bovine immunoglobulin preparations, primarily containing igg, in such conditions as irritable bowel syndrome with diarrhea (ibs-d) and hiv-associated enteropathy [59,61]. |
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