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PedAM

Pediatric Disease Annotations & Medicines




Disease iron deficiency anemia
Phenotype C0022661|chronic renal disease
Sentences 1
PubMedID- 24790431 Iron oxide-based uspios have been widely used for the characterization of nodal metastasis in various abdomino-pelvic malignancies.22,23 ferumoxytol is a newer uspio, which is fda-approved for the treatment of iron deficiency anemia in patients with chronic renal disease and has also been utilized to image inflammation in animal studies.24–26 another super paramagnetic iron oxide-ferucarbotran was recently studied by kakite et al in animal models to evaluate ablated liver parenchyma.27 this observation was further validated in human studies, which demonstrated the use of impaired clearance of ferucarbotran to assess ablative margin and predict residual or recurrent tumor in patients undergoing radiofrequency ablation for hepatocellular carcinoma.28,29 ferumoxytol has been used for tumor imaging before by muldoon et al for intracerebral tumors in animal models.

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