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PedAM

Pediatric Disease Annotations & Medicines




Disease interstitial nephritis
Phenotype C0033687|proteinuria
Sentences 4
PubMedID- 26266393 The most common renal manifestation of igg4-related disease is tubulointerstitial nephritis marked with proteinuria, hematuria, decreased kidney function, hypocomplementemia, and radiologic abnormalities.
PubMedID- 25880729 Besides producing a reversible renal failure, nsaids are known to cause acute interstitial nephritis (ain) with hematuria, proteinuria and flank pain [14] as well as acute tubular necrosis (atn).
PubMedID- 22382248 interstitial nephritis with proteinuria >1 g/day is uncommon and almost always the result of drug-induced atin with an associated minimal change glomerulonephritis (gn).
PubMedID- 25684013 For example, drug exposure can result in the release of permselectivity promoting factors from activated inflammatory or immune cells, causing mcd.13 another possible mechanism of mcd is via direct toxin effects on glomerular epithelial cells, resulting in abnormal permeability and effacement of the foot processes.13 neugarten, et al.7 reported the first case of rifampicin-induced nephrotic syndrome, and described the patient as having acute interstitial nephritis with heavy proteinuria and effacement of the glomerular epithelial cells.

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