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PedAM

Pediatric Disease Annotations & Medicines




Disease interstitial lung disease
Phenotype C0009782|connective tissue disease
Sentences 14
PubMedID- 26443305 Yamamoto has investigated the association between connective tissue disease with interstitial lung disease and tumour maker ca19–9, and found that ild increased as the expression of ca19–9 increased and that the level of ca19–9 was inversely related with dlco25.
PubMedID- 22390563 Treatment of interstitial lung diseases associated with connective tissue diseases.
PubMedID- 26424433 The human ethics review committee of kagoshima university school of medicine approved the study protocol and all participants provided written informed consent prior to enrolment in the study.table 1characteristics of patients with interstitial lung disease associated with connective tissue disease (ctd-ild), undifferentiated ctd-ild (uctd-ild), chronic fibrosing interstitial lung disease (cfip), and control subjectscontrolcfipuctd-ildctd-ildp-valuesubjects, n26191633age, years64 (59–81)67 (54–80)70 (53–79)63 (39–83)0.0265females, n (%)16 (61)3 (15)8 (50)22 (66)0.0032smoking status former smoker, n (%)7 (26)12 (63)8 (50)11 (33)0.0617 current smoker, n (%)1 (3)2 (10)1 (6)0 (0)0.3250 pack-years0 (0–40)30 (0–150)5 (0–70)0 (0–100)0.0035pa, o2 mmhg83.6 (62.4–111.7)72.5 (58.8–86.6)79.2 (42.3–105.2)0.1413kl-6, u · ml−1261 (140–491)1581 (304–8298)1045 (363–4560)1117 (289–3943)<0.0001sp-d, ng · ml−132.3 (8.6–126.0)292.5 (32.3–1070)206.0 (88.6–405)175.0 (31.2–994.0)<0.0001baff, ng · ml−10.6 (0.5–0.9)1.0 (0.3–1.9)1.8 (1.0–2.3)2.0 (0.6–16.7)<0.0001vc, l1.9 (0.9–3.1)2.1 (0.9–3.1)2.0 (1.0–3.5)0.9213vc, % pred59.8 (35.4–128.2)69.2 (37.9–97.4)65.4 (41.3–104.1)0.3390dl,co, ml · min−1 · mmhg−19.3 (3.4–15.4)8.9 (4.5–16.9)10.8 (4.6–16.9)0.6097dl,co, %pred63.2 (43.5–125.4)60.4 (26.9–74.4)64.7 (29.0–109.4)0.2751data are presented as counts (n) or medians and ranges (minimum-to-maximum values), unless otherwise stated.
PubMedID- 24003680 In the later course of the disease clinical picture of mixed connective tissue disease associated with interstitial lung disease, with a dominant picture of systemic sclerosis have emerged.
PubMedID- 25995034 Objective: to examine clinical utility of 18f-flurodeoxyglucose (fdg)-positron emission tomography (pet)/ct for assessment of interstitial lung disease (ild) in patients with connective tissue diseases (ctds).
PubMedID- 22967460 In a retrospective cohort study of patients with progressive interstitial lung disease (ild) associated with connective tissue disease not responding to conventional immunosuppressive regimens, rituximab improved lung function in seven of eight patients [24].
PubMedID- 20936629 Objective: connective tissue diseases (ctds) are associated with several interstitial lung diseases.
PubMedID- 21597375 Purpose of review: there is no specific therapy for interstitial lung disease associated with connective tissue diseases (ctds-ild), a potentially fatal condition for some of these patients.
PubMedID- 23457161 interstitial lung disease associated with connective tissue disease has been definitely established to have a better long-term survival than ipf.
PubMedID- 23289473 [interstitial lung disease associated with connective tissue diseases: diagnosis and treatment approaches].
PubMedID- 25972968 Lung-dominant connective tissue disease among patients with interstitial lung disease: prevalence, functional stability, and common extrathoracic features.
PubMedID- 22282550 In very severe interstitial lung disease associated with connective tissue disease (ctd-ild), progressing despite maximal conventional immunosuppression, there is no effective medical rescue therapy.
PubMedID- 24252051 Increased serum concentration of baff/april and iga2 subclass in patients with mixed connective tissue disease complicated by interstitial lung disease.
PubMedID- 21645423 Undifferentiated connective tissue disease presenting with prevalent interstitial lung disease: case report and review of literature.

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