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PedAM

Pediatric Disease Annotations & Medicines




Disease insulinoma
Phenotype C0020598|hypoglycemia
Sentences 19
PubMedID- 22525212 To our knowledge, this is the first report to provide evidence that strontium-89 can be useful in controlling intractable hypoglycemia in patients with malignant insulinoma with bone metastases.
PubMedID- 25667631 In the case that a patient presents with fasting hypoglycemia, the possibility of an insulinoma should be always considered.
PubMedID- 25892896 Here we report the case of a 79-year-old female who presented with repeated episodes of hypoglycemia and was diagnosed with insulinoma based on laboratory and imaging examinations.
PubMedID- 22844555 insulinoma often presents with symptoms of hypoglycemia caused by an elevation of insulin levels in the blood.
PubMedID- 26107678 However, we believe that hypoglycemia in insulinoma patients is unlikely to produce rbd arising from rem sleep.
PubMedID- 26113980 Everolimus has been shown to affect glycemic control and was utilized to resolve hypoglycemia in insulinoma patients (7); this effect was not attributed to a reduction in tumor size (7)(8).
PubMedID- 24396652 The main causes of hypoglycemia combined with hyperinsulinemia are insulinoma, inappropriate use of antidiabetic agents, and autoimmune hypoglycemia.
PubMedID- 23738155 A case of inoperable malignant insulinoma with resistant hypoglycemia who experienced the most significant clinical improvement with everolimus.
PubMedID- 23392213 Background: refractory hypoglycemia in patients with metastatic insulinoma is an important cause of morbidity and mortality.
PubMedID- 20052354 Regarding the endocrine function, 6 patients had diabetes mellitus and 2 patients had insulinoma with hypoglycemia preoperatively in organ-preserving pancreatectomy group.
PubMedID- 24130355 Further support for this concept derives from recovery of iah and defective counterregulation after eliminating recurrent hypoglycemia in people with insulinoma (13,14) and in people with t1d after pancreas (15,16) and islet cell transplantation (17), as well as through adherence to treatment protocols aimed at meticulous prevention of hypoglycemia (18–21).
PubMedID- 25844345 A diagnosis of insulinoma was suspected in patients with symptomatic fasting hypoglycemia, which includes: (1) symptoms and signs of hypoglycemia, (2) concomitant plasma glucose level of ≤45 mg/dl, and (3) reversibility of symptoms with glucose administration.
PubMedID- 26425596 Attenuated counterregulatory hormonal responses to severe hypoglycemia occur in patients with insulinoma,7-11 in infants with phhi,12,13 and in diabetic patients treated with excess exogenous insulin.14,15 insulinoma resection mitigates hyperinsulinemic hypoglycemic episodes and is associated with restoration of physiologic counterregulatory hormone response to hypoglycemia.7-11 we report 3 individuals who underwent rygb complicated by niphs and subsequently developed adrenal insufficiency (ai).
PubMedID- 25381469 Although insulinomas typically present with fasting hypoglycemia, it is important to consider insulinoma in the differential diagnosis of patients presenting exclusively with postprandial hypoglycemia.
PubMedID- 21247848 Conclusion: the orally administered drug everolimus controlled hypoglycemia due to a malignant insulinoma in a patient with prior insulin-requiring diabetes.
PubMedID- 21826148 Taken together, these results suggested that inappropriate endogenous hyperinsulinemia was responsible for her hypoglycemia, possibly due to insulinoma, nesidioblastosis, or β cell dysfunction.
PubMedID- 24358830 Furthermore hypoglycemia due to an insulinoma especially in a young age group comes little lower in the list of other possible causes.
PubMedID- 23237225 Once hypoglycemia symptoms due to a suspected insulinoma are confirmed, the tumor should be localized prior to attempts at surgical resection.
PubMedID- 20930440 Glucose-responsive insulinoma in a patient with postprandial hypoglycemia in the morning.

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