PedAM
Pediatric Disease Annotations & Medicines
| Disease | influenza |
| Phenotype | C0042214|vaccinia |
| Sentences | 2 |
| PubMedID- 23272943 | We previously used rvj1175 expressing the potential cross-protective antigens of np, matrix protein 1 (m1) and polymerase basic 1 (pb1) of influenza a/jingke/30/95(h3n2) with the vaccinia virus tiantan strain to induce cross-protection in balb/c mice, the results indicated that np is the most effective antigen among the antigens we tested, and the survival rate of the rvj1175np immunized mice could achieved as high as almost 100% against the lethal challenge of influenza influenza virus a/pr/8/34 (h1n1) with a challenge dose ranged from 1ld50 to 5ld50[20]. |
| PubMedID- 20483407 | Moreover, the recognition is cross-reactive between various subtypes of influenza, but not with vaccinia virus. |
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