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PedAM

Pediatric Disease Annotations & Medicines




Disease influenza
Phenotype C0032285|pneumoniae
Sentences 27
PubMedID- 22162775 To investigate gene regulation when h. influenzae was cultured with s. pneumoniae, the transcript for nthi type iv pili (pila) and was examined and compared to expression of nthi 16s rrna as a reference gene.
PubMedID- 25867910 High rate of mycoplasma pneumoniae co-infection with influenza viruses might contribute to severe disease in the hospitalized children.
PubMedID- 21214902 Bacterial pneumoniae in association with influenza has been considered a important factor leading to poor patients outcomes in prior pandemics [26].
PubMedID- 21747847 Are close behind s. pneumoniae as a cause of coinfection with influenza virus.
PubMedID- 24498274 (n = 1); influenza a with streptococcus pneumoniae (n = 1).
PubMedID- 24453496 Promising candidate antigens for vaccination have been identified in s. pneumoniae (the commonest cause of aom), nontypeable h. influenza, and m catarrhalis.
PubMedID- 23326226 When s. pneumoniae was co-colonized with an h. influenzae strain, the density of s. pneumoniae was lower than when inoculated alone, and this proved to be fully dependent on complement- and neutrophil-mediated killing of pneumococci [32], [33].
PubMedID- 25887603 Viral–bacterial coinfections were established in 51 (31%) of patients; the most common combinations were s. pneumoniae with influenza viruses (16 of 51 patients, 31%) or rhinovirus (14 of 51, 27%) (additional file 1: table s1).table 4distribution of single and multiple bacterial and viral agents detected in 167 adults with an etiologically established diagnosis of community-acquired pneumoniabacterial agentspure bacterial infections(n = 75)viral–bacterial coinfections(n = 51)totalonly oneplus other bacteriumplus virusaplus virus and other bacteriumn (%)streptococcus pneumoniae37829781 (49)bordetella pertussis244515 (9)haemophilus influenzae255214 (8)mycoplasma pneumoniae7310 (6)chlamydophila pneumoniae5117 (4)legionella pneumophila2327 (4)enterobacteriaceae1326 (4)moraxella catarrhalis2125 (3)miscellaneousb1113 (2)haemophilus parainfluenzae112 (1)subtotal cases with bacteria60126 (75)cviral agentspure viral infections(n = 41)viral–bacterial coinfections(n = 51)totalonly oneplus other virusplus bacteriumaplus bacterium and other virusn (%)influenza viruses15d221240 (24)rhinovirus12215332 (19)parainfluenza viruses3418 (5)respiratory syncytial virus3227 (4)metapneumovirus3317 (4)enterovirus2125 (3)adenovirus11 (0.6)subtotal cases with viruses3992 (55)cnote: drammen, norway, january 2008–january 2011.aone or two.bgroup a streptococcus; prevotella spp.
PubMedID- 20979628 Fatal co-infections of influenza virus with streptococcus pneumoniae have been described in mice since the early eighties [6], and have been reported following in clinical outbreaks [7].
PubMedID- 20178591 In mixed-species introductions, s. aureus or s. pneumoniae facilitated the invasion of another h. influenzae population; for other pairs the interaction was antagonistic and immune-mediated.
PubMedID- 20955369 pneumoniae with influenza a virus (p=0.004).
PubMedID- 23531034 Currently, streptococcus pneumoniae along with nontypeable haemophilus influenzae are the major pathogens of aom cases [2,3].
PubMedID- 23467809 This phenomenon was further supported by our in vitro experiments demonstrating that incubation of neutrophils isolated from influenza-infected mice with s. pneumoniae led to partial nets degradation.
PubMedID- 25705586 The bacterial carriage of s. pneumoniae was negatively associated with h. influenzae in stages 1 and 4. however, higher rates of s. pneumoniae colonized in stages 2 and 3, with higher rates of h. influenzae infection in the same stages (figure 1c).
PubMedID- 24355091 Co-colonization by haemophilus influenzae with streptococcus pneumoniae enhances pneumococcal-specific antibody response in young children.
PubMedID- 21057815 Streptococcus pneumoniae) are known in patients with influenza a infections to not only aggravate the disease course, but also serve as a possible hus trigger.
PubMedID- 24727518 Streptococcus pneumoniae concomitant with haemophilus influenzae (36%) and rhinovirus (16%) was very common, whereas atypical pathogens (only mycoplasma pneumoniae) were rare (6%).
PubMedID- 21895747 Coli) and klebsiella pneumoniae are not associated with influenza infection.
PubMedID- 21612658 In addition, co-infection of influenza patients with s. pneumoniae is known to exacerbate their clinical outcome [4]: for example, 50% or more of the flu-associated mortality in the 1918-1919 spanish flu epidemic is believed to have resulted from pneumococcal superinfections [8,9], and s. pneumoniae co-infection has been specifically correlated with the severity of the recent h1n1 pandemic influenza [10].
PubMedID- 26543526 pneumoniae seen in 70% of patients, h. influenzae bacteremia, n. meningitides and capnocytophaga cynodegmi.
PubMedID- 23260033 In japan, a fatal case of influenza pneumonia combined with streptococcus pneumoniae and m. tuberculosis infection in a patient with diabetes mellitus was reported (7).
PubMedID- 21760867 The most frequent combinations have been streptococcus pneumoniae with influenza a virus or hrv.
PubMedID- 21689403 However co-carriage of s. pneumoniae with h. influenzae, s. aureus and m. catarrhalis has not been described in west africa.
PubMedID- 25897241 Ceftaroline activity was high against beta-haemolytic streptococci, s. pneumoniae (regardless of penicillin-susceptibility status), h. influenza, and moraxella catarrhalis (m. catarrhalis) (regardless of beta-lactamase activity).
PubMedID- 25827870 influenza a paired with s. pneumoniae had higher proportions of chills and rigors than their respective mono-pathogens (p = 0.03, p = 0.009).
PubMedID- 26351646 It has been shown that h. influenzae when colonising with s. pneumoniae may outcompete them for survival through signaling of nucleotide-binding oligomerisation domain-1 (nod1) to facilitate clearance of s. pneumoniae [81], but virulent s. pneumoniae serotypes show resistance to host cell-mediated clearance as a mechanism to overcome these attacks [82].
PubMedID- 25151773 pneumoniae (prsp); 26.4% of haemophilus influenzae was beta-lactamase negative ampicillin-resistant h.

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