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PedAM

Pediatric Disease Annotations & Medicines




Disease infertility
Phenotype C0042341|varicoceles
Sentences 7
PubMedID- 23346528 Studies that have previously been carried out abroad have reported that the percent of varicoceles among patients with male infertility is 42.2% [23].
PubMedID- 25890347 Based on the number of peptides and peptide coverage number in the triple run, we narrowed down the choice of potential candidate proteins that could be identified as our first choice of potential biomarkers in identifying unilateral varicoceles associated with male infertility (table 5).
PubMedID- 23503958 This meta-analysis concluded that surgical and radiological treatment of varicoceles in men with otherwise unexplained infertility could not be recommended; however, the meta-analysis was criticized because it included studies of men with normal semen parameters and subclinical varicoceles.
PubMedID- 24712000 Additional hypotheses on the mechanisms of infertility in men with varicoceles are associated with increased oxidative stress and decreased antioxidant capacity.
PubMedID- 25598931 varicoceles have been associated with male infertility, although the exact cause-and-effect relationships have not been established.
PubMedID- 25165747 Thirty-three and twenty-one were from the patients with varicoceles and idiopathic causes of infertility, respectively.
PubMedID- 22162682 Improvement in semen parameters was also detected, but the authors emphasized pregnancy as being the ultimate goal for infertility patients with treated varicoceles as semen parameters demonstrated extensive intra- and interindividual variability as well as overlapping between fertile and infertile men.

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