PedAM
Pediatric Disease Annotations & Medicines
| Disease | infertility |
| Phenotype | C0028754|obesity |
| Sentences | 18 |
| PubMedID- 24374455 | This study has concluded that obesity is associated with infertility in men and women. |
| PubMedID- 23874146 | obesity has been associated with infertility and an increased risk of menstrual irregularity or amenorrhea [9]. |
| PubMedID- 25780937 | infertility associated with obesity is characterized by abnormal hormone release from reproductive tissues in the hypothalamus, pituitary, and ovary. |
| PubMedID- 24379345 | obesity-induced infertility and hyperandrogenism are corrected by deletion of the insulin receptor in the ovarian theca cell. |
| PubMedID- 22110473 | Briefly, at the maternal level, obesity increases the risk of menstrual disorders [12], infertility [13], miscarriage [14], pregnancy-induced hypertension and preeclampsia [15], gdm [16], induction of labour and caesarean section [17], and haemorrhage, infection, and venous thromboembolism. |
| PubMedID- 23074007 | No evidence-based treatment that increases the likelihood of pregnancy for the infertility associated with male obesity has been demonstrated to date. |
| PubMedID- 20648018 | The risk factors included in the ukctocs questionnaire were selected >10 years ago and other risk factors for oc have since been described including obesity, current use of hormone replacement therapy, infertility, perineal talc use and endometriosis. |
| PubMedID- 23230382 | obesity is associated with menstrual disorders, infertility and sporadic miscarriages. |
| PubMedID- 22783836 | From a reproductive standpoint, obesity has been associated with infertility and hypogonadism. |
| PubMedID- 24173881 | Indeed, it has been well described that undernutrition or obesity can lead to subfertility or infertility in humans. |
| PubMedID- 22844280 | Current studies revealed that the risk of infertility increases with obesity grade [18] regardless of age and female partner's bmi and smoking habits of both partners [19]. |
| PubMedID- 21185491 | In case of infertility associated with obesity or cigarette smoking, physicians have to inform their patient about the benefits of smoking cessation and weight loss. |
| PubMedID- 26120850 | Fat/fat mice, which have a naturally-occurring point mutation (ser202pro) inactivating cpe, have slowly developing, adult-onset obesity with hyperproinsulinaemia and infertility [4]. |
| PubMedID- 25161489 | The findings of this study may be limited by the smallsample size; the association of obesity with tubalinfertility may be validated in the larger study to follow.the study will include evaluation of cellular as well ashumoral pathologic response found associated withtubal infertility, and will hopefully shed more light onthe aetiopathogenesis of infertility. |
| PubMedID- 22980196 | Increased infertility associated with diet induced obesity or central leptin resistance are likely mediated through the kisspeptin-gnrh pathway. |
| PubMedID- 24250624 | In many women with pcos, insulin resistance, obesity, disorders of lipid metabolism and infertility can also be found. |
| PubMedID- 20816095 | Rescue of obesity-induced infertility in female mice due to a pituitary-specific knockout of the insulin receptor. |
| PubMedID- 24551574 | Polycystic ovary syndrome (pcos) is a common endocrine disorder, characterized by clinical and/or biochemical hyperandrogenism and chronic anovulation, polycystic ovaries in ultrasonography findings, and frequently morbid obesity, which is associated with infertility, menstrual dysfunction, hirsutism and frequent miscarriages (1, 2). |
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