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PedAM

Pediatric Disease Annotations & Medicines




Disease infertility
Phenotype C0027086|myoma
Sentences 2
PubMedID- 26321611 In 5 to 10% of cases, infertility is associated with myoma and in 1 to 3% myoma is the only infertility factor.
PubMedID- 24168009 Athough the exact mechanism of infertility in women with myoma is unknown, the theories of pathogenic mechanisms include mechanical blockage of tubal ostia impairing sperm or embryo transport through the fallopian tubes, abnormal vascularization, abnormal endometrial development, chronic intracavitary inflammation, an abnormal endocrine milieu, and increased uterine contractility[3].

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