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PedAM

Pediatric Disease Annotations & Medicines




Disease infertility
Phenotype C0020514|hyperprolactinemia
Sentences 4
PubMedID- 26375566 Initially, the state of hyperprolactinemia was correlated with infertility in humans based on the negative effects on ovarian function, leading to changes in the serum levels of sex hormones 6-7. prolactin acts systemically through its receptor in target organs, such as the uterus, cornea and lacrimal gland 1,12-16,. in the present study, the serum prolactin levels were elevated in all the metoclopramide-treated animals.
PubMedID- 21170594 Treatment of hyperprolactinemia is indicated because of resulting infertility, gonadal dysfunction and osteoporosis.
PubMedID- 24062868 hyperprolactinemia presents with hypogonadism, infertility, amenorrhea, and galactorrhea.
PubMedID- 23678832 Material and methods: during the 10 years period, we have studied 87 patients investigated for infertility causes and with hyperprolactinemia findings, in our patients we have controled the serum prolactin levels, performed mri of hypophysis, evaluated menstrual cycle disturbances and galactorrhea.

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