PedAM
Pediatric Disease Annotations & Medicines
| Disease | il13 gene |
| Phenotype | C0004096|asthma |
| Sentences | 100 |
| PubMedID- 25852853 | More importantly, according to the “united airways” principle there is a significant correlation of allergic rhinitis with asthma, prompting the aria (allergic rhinitis and its impact on asthma) –initiative by the world allergy organization [7]. |
| PubMedID- 24679069 | The possible preventive effect of slit on the development of asthma in children with allergic rhinitis is the primary aim of a large double-blind placebo-controlled study currently in progress (the gap study) [119]. |
| PubMedID- 24401902 | Prevalence and clinical relevance of allergic rhinitis in patients with classic asthma and cough variant asthma. |
| PubMedID- 21507261 | Thirty-two non-smoking subjects were recruited: 19 had mild stable asthma associated with allergic rhinitis (a) and 13 had allergic rhinitis without asthma (r). |
| PubMedID- 24274226 | A hospital-based survey on the prevalence of bronchial asthma in patients with allergic rhinitis in southern china. |
| PubMedID- 22166157 | allergic rhinitis frequently coexists with asthma [6], and it is often a long-standing condition that goes undetected in the primary-care setting. |
| PubMedID- 22170807 | Subjects aged 12-17 years, with mild-to-moderate asthma, intermittent allergic rhinitis and >/= 10% fall in fev(1) at a screening exercise challenge were randomized to 22 +/- 3 days treatment with intranasal fluticasone furoate or placebo. |
| PubMedID- 21261960 | Our cohort study of non-asthmatic adults with allergic rhinitis and followed up for 10 years shows that smoking can predict not just asthma incidence [13], but also severity and level of control of the disease (this paper). |
| PubMedID- 24284354 | By contrast, only maternal and paternal history of asthma with allergic rhinitis predicted peanut allergy in the infant. |
| PubMedID- 24945941 | Atopic, non-atopic asthma and asthma associated with allergic rhinitis (ar) showed elevated levels of eco. |
| PubMedID- 26214692 | The relationship between current rhinitis symptoms and feno is biologically plausible, because allergic rhinitis is associated with poor asthma control in children [26]. |
| PubMedID- 22166078 | Immunotherapy may also reduce the risk for the future development of asthma in patients with allergic rhinitis [5]. |
| PubMedID- 21356099 | By contrast, allergic rhinitis (with or without asthma) was positively linked to icos expression. |
| PubMedID- 23268480 | Managing co-morbid asthma with allergic rhinitis: targeting the one-airway with leukotriene receptor antagonists. |
| PubMedID- 21530815 | Disease-modifying actions include blocking development of new sensitivities in monosensitized patients, blocking progression to asthma in patients with allergic rhinitis, and persistence of treatment effects for up to 7 to 10 years after an initial course. |
| PubMedID- 26072703 | Poorly controlled allergic rhinitis may be associated with worsening asthma symptoms over time. |
| PubMedID- 23282652 | Thus, slit can be used for allergic rhinitis in children with or without asthma but should not be suggested as monotherapy for treating asthma. |
| PubMedID- 21764573 | Family history of allergy yielded a higher or for asthma with allergic rhinitis than with asthma with chronic rhinosinusitis (or 7.15 vs. |
| PubMedID- 24075536 | This may have implications for the therapy of seasonal allergic rhinitis with and without asthma in terms of promoting long-term anti-inflammatory treatment. |
| PubMedID- 20835305 | Another study evaluated the economics of slit in patients with pollen allergy and suffering from allergic rhinitis alone or associated with asthma compared with standard case controls. |
| PubMedID- 23517484 | There was a significant relation between asthma control and rate of allergic rhinitis, atopic dermatitis, and gastroesophageal reflux as well as depression with more frequent comorbidities in patients with uncontrolled asthma. |
| PubMedID- 22073091 | Bronchial asthma in patients with allergic rhinitis) and the expansion of sensitization can be limited. |
| PubMedID- 20463255 | There are compelling epidemiologic links between mold (fungal) allergy and illnesses such as asthma and "asthma with allergic rhinitis." fungal allergy is more prevalent in areas of high ambient mold spore concentrations. |
| PubMedID- 21761714 | Method: genmapp software was used to analyze the expression profile of nasal mucosa of seasonal allergic rhinitis(sar) and sar associated with asthma of oligonucleotide microarray (affymetrix hg-u133-plus2). |
| PubMedID- 26340660 | For instance, apart from a higher prevalence of allergic rhinitis in patients with asthma [1], recent studies have further shown that chronic rhinosinusitis (crs) was fairly common in patients with bronchiectasis [2] and posed adverse impacts on lung function [2], quality of life [3,4] and the lost sense of smell [4,5]. |
| PubMedID- 22739747 | Allergen immunotherapy (ait) is the only treatment that may affect the natural course of allergic disease and it may prevent the later development of asthma in patients with allergic rhinitis. |
| PubMedID- 22213738 | Objective: to examine the prevalence of allergic rhinitis in children with asthma, and the impact of the disease and its treatment on asthma control. |
| PubMedID- 24019844 | The prevalence of allergic rhinitis in children with asthma was 64.3% and that of asthma in children with allergic rhinitis was 21.6%. |
| PubMedID- 20542677 | allergic rhinitis alone or with asthma is associated with an increased risk of sickness absences. |
| PubMedID- 24066007 | Since allergic rhinitis highly coexisted with asthma, the use of single diagnosis was helpful in focusing on prescriptions for asthma. |
| PubMedID- 23379115 | The different ages, living environment, family history, history of eczema and allergic rhinitis children with asthma were related with the pathogenesis and development of ar in childhood. |
| PubMedID- 22500494 | In asthmatic adults with concomitant allergic rhinitis asthma control is less manageable while there is a higher rate of asthma exacerbations and emergency room visits [6]. |
| PubMedID- 25378841 | A total of 90 subjects (36 females and 54 males) aged between 6-38 years were evaluated and they were divided into 4 groups: group a - 25 bronchial asthma (without allergic rhinitis); group b - 25 allergic rhinitis (without bronchial asthma); group c - 25 bronchial asthma with allergic rhinitis and group d - 15 controls. |
| PubMedID- 22707776 | The pulmonologist diagnosed the condition as allergic rhinitis with bronchial asthma and prescribed bronchodilators. |
| PubMedID- 22950032 | The prevalence of allergic rhinitis in adults with asthma was reported to be 60%-80% in korea,32 and this condition was also closely associated with more frequent asthma attacks, er visits, and poor asthma control.33,34 elderly women with asthma were particularly likely to have weakened bone structures after a 6-month treatment regimen with ics, this was replicated in our data (degenerative arthritis and/or osteoporosis, 71.2% in female vs. 28.6% in male, p<0.001).35 these findings suggest that comorbid conditions are common among elderly patients with asthma and that evaluation and proper control of these conditions will improve asthma control in this population. |
| PubMedID- 24282527 | Using correction for multiple testing, 1988 genes were differentially expressed between healthy lower and upper airway epithelium, whereas in allergic rhinitis with or without asthma this was only 40 and 301 genes, respectively. |
| PubMedID- 26213497 | More importantly, there is evidence that ait can modify the natural history of allergic disease, for instance preventing the onset of asthma in patients with allergic rhinitis and/or maintaining a long-lasting effect [10]. |
| PubMedID- 20462426 | She had moderately severe allergic rhinitis with intermittent asthma, but used nasal fluticasone propionate occasionally for relief of the most severe symptoms. |
| PubMedID- 23265261 | This finding was surprising as allergic rhinitis is frequently associated with asthma and asthma prevalence is about 10% of the general paediatric population. |
| PubMedID- 22359883 | allergic rhinitis is often associated with allergic asthma, either preceding it, or developing later and making it more difficult to treat. |
| PubMedID- 24396984 | The studies thus far available showed that this treatment, in both forms of subcutaneous immunotherapy (scit) and sublingual immunotherapy (slit) is able to prevent the development of asthma in patients with allergic rhinitis and the occurrence of new sensitizations in patients monosensitized. |
| PubMedID- 23856015 | Co-morbidity of allergic rhinitis with asthma is common and is associated with poor asthma outcomes[8-10]. |
| PubMedID- 22507625 | Methods: a case-control comparison was performed in a cohort of 279 ar patients, 197 allergic rhinitis with asthma (ar-a) patients and 281 control chinese subjects, to investigate associations between 19 tagging single-nucleotide polymorphisms (snps) in il-17a and il-17f gene regions and manifestation of ar or ar-a. |
| PubMedID- 22978345 | This was then tested on 150 asthma patients with allergic rhinitis. |
| PubMedID- 25565052 | During inflammation, inducible nitric oxide synthase expression increases in response to specific and nonspecific stimuli.21 in our study, feno was significantly increased in asthma patients with allergic rhinitis (p < 0.01) or allergic conjunctivitis. |
| PubMedID- 22405116 | Despite a high prevalence of both gastro-oesophageal reflux and allergic rhinitis among patients with asthma, treatment with proton-pump inhibitors or nasal corticosteroids does not reduce the rate of asthma exacerbations. |
| PubMedID- 24404392 | Compared to asthma patients, subjects with allergic rhinitis were more sensitized to allergens.13,25 moreover, sensitization to outdoor allergens is associated with allergic rhinitis, rather than asthma;13,18 in particular, pollens were major sensitizing allergens in patients with allergic rhinitis.13,34 factors that influenced the clinical significance of aeroallergens include concentration, particle size, and exposure duration of the aeroallergens.35,36 airborne pollens with diameters larger than those of house dust mite particles may not reach the lower respiratory tract; however, conjunctival and upper respiratory tract mucosa can be exposed to large amounts of aeroallergens, even large allergens such as pollens. |
| PubMedID- 23840530 | In total, 58 children were recruited: 15 asthmatic children; 9 with allergic rhinitis; 10 with asthma and allergic rhinitis; and 24 healthy children. |
| PubMedID- 23413909 | Both modes of allergen administration during immunotherapy have been shown not only to reduce symptoms and the need for medication, but also to prevent the development of additional sensitivities in monosensitized patients, as well as asthma development in patients with allergic rhinitis, with a long-lasting effect after the completion of several years of treatment. |
| PubMedID- 20459697 | Exclusion criteria were asthma, a history of perennial (persistent) allergic rhinitis or a positive skin prick test to perennial allergens, and other chronic nasal disease or major nasal structural abnormalities. |
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