PedAM
Pediatric Disease Annotations & Medicines
| Disease | iga glomerulonephritis |
| Phenotype | C0033687|proteinuria |
| Sentences | 26 |
| PubMedID- 23977072 | A report from a study carried out in china stated that, among iga nephropathy patients with proteinuria of <0.4 g/day, gfr ≥90 ml/min/1.73 m2, and normotension, proteinuria increased in 46% of patients, hypertension was developed in 38%, and renal insufficiency in 24% during the mean follow-up duration of 111 months [13]. |
| PubMedID- 21655166 | [2122] the ii genotype has been reported to be associated with more favorable prognosis and decreased proteinuria in patients with iga nephropathy. |
| PubMedID- 23502465 | Reported a down-regulation of nestin expression in fsgs, mn and iga nephropathy with proteinuria, and the glomerular nestin expression levels correlated inversely with the 24-hour urine protein results [11]. |
| PubMedID- 23331443 | Conclusion: for early iga nephropathy patients with minimal proteinuria, normal blood pressure, and normal renal function, treatment with 2.5 mg/daily of ramipril for 5 years does not offer any benefit. |
| PubMedID- 26289088 | Background: sometimes, acute and progressive proteinuria increases occur in patients with iga nephropathy (igan) after favorable long-term clinical courses of >10 years, but their clinical and histological characteristics are not well understood. |
| PubMedID- 23675422 | The primary objective of the present study is to evaluate the safety and short-term efficacy of aliskiren, a direct renin inhibitor, on proteinuria reduction in patients with iga nephropathy. |
| PubMedID- 26435893 | The original oxford classification cohort demonstrated that mesangial hypercellularity, segmental sclerosis and endocapillary proliferation were histopathological variables associated with proteinuria (working group of the international iga nephropathy network and the renal pathology society et al. |
| PubMedID- 22019331 | Oral calcitriol for reduction of proteinuria in patients with iga nephropathy: a randomized controlled trial. |
| PubMedID- 22086123 | Reported on the natural history of mild or early-stage iga nephropathy in patients with proteinuria <0.4 g/day over an observation period of 7 years [5]. |
| PubMedID- 23741418 | Emerging clinical and animal studies have demonstrated that vitamin d and its analog reduce proteinuria in patients with iga nephropathy [2], non-dialysed chronic kidney disease stage 4–5 [3], [4], diabetic nephropathy [5], and animal models such as subtotally nephrectomized model [6], diabetic nephropathy model [7], adriamycin-induced nephropathy [8], puromycin-induced nephropathy [9], [10]. |
| PubMedID- 23049672 | Oral calcitriol treatment reduced proteinuria in patients with iga nephropathy [172]. |
| PubMedID- 26239462 | Urinary ngal levels also correlated with the degree of proteinuria in patients with iga nephropathy [16] and membranous nephropathy [14,15]. |
| PubMedID- 20594038 | The authors measured the extent of foot process effacement in 100 iga nephropathy cases with proteinuria and correlated it with the amount of proteinuria. |
| PubMedID- 21533280 | Background: studies have shown that steroids can improve kidney survival and decrease the risk of proteinuria in patients with immunoglobulin a nephropathy, but the overall benefit of steroids in the treatment of immunoglobulin a nephropathy remains controversial. |
| PubMedID- 22456060 | Tacrolimus improves the proteinuria remission in patients with refractory iga nephropathy. |
| PubMedID- 24707402 | Before the eradication therapy the mean proteinuria of patients with mn, iga nephropathy and fsgs were 2.42 ± 3.24 g/day, 2.12 ± 1.63 g/day and 1.80 ± 1.32 g/day, respectively. |
| PubMedID- 23197956 | Successful treatment of adult iga nephropathy with nephrotic-level proteinuria by combination therapy including long-term coadministration of mizoribine. |
| PubMedID- 23713873 | Calcitriol (0.5 microg calcitriol twice per week) has been effective in decreasing proteinuria in patients with iga nephropathy. |
| PubMedID- 26527894 | Most of the study population included diabetic nephropathy, lupus nephropathy, and iga nephropathy with persistent proteinuria, and received corticosteroid therapy, confirming the need for validating gfr equations in this setting. |
| PubMedID- 23610524 | One case of berger disease was observed in a patient with late combined proteinuria and macroscopic hematuria, although renal biopsy did not reveal typical lesions. |
| PubMedID- 20843592 | Conclusions: thujone-free wormwood with its favorable safety profile can be an alternative supplement to manage proteinuria in patients with iga nephropathy. |
| PubMedID- 23557791 | Aims: both steroid pulse (sp) monotherapy and the combination of tonsillectomy and sp therapy (tsp) are effective for achieving clinical remission (cr), defined as negative hematuria and proteinuria, in patients with iga nephropathy (igan). |
| PubMedID- 24721885 | Conclusions: the findings in this cohort and previous studies suggest that rare cases of mild iga nephropathy with nephrotic range proteinuria exhibit a clinical presentation, biopsy findings, treatment response, and outcome more typical of iga nephropathy with superimposed minimal change disease. |
| PubMedID- 24131475 | Conclusion: immunoglobulin a nephropathy patients with lower proteinuria had higher galnac exposure rates. |
| PubMedID- 23326865 | In two small studies, the addition of aliskiren to arb was shown to decrease proteinuria in subjects with iga nephropathy and various forms of primary glomerulonephritis [13, 14]. |
| PubMedID- 20826744 | Conclusions: among patients with primary glomerulopathy and nephrotic-range proteinuria, normoalbuminaemia is associated with iga nephropathy. |
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