PedAM
Pediatric Disease Annotations & Medicines
| Disease | hypothyroidism |
| Phenotype | C0242231|coronary artery stenosis |
| Sentences | 1 |
| PubMedID- 22291465 | However, due to the positive inotropic and chronotropic effects of thyroid hormone on the heart, starting a full dose of levothyroxine could precipitate acute coronary syndrome in hypothyroid patients with previously silent coronary artery stenosis.96 therefore, newly diagnosed hypothyroid patients with ischemic heart disease should be started on a small dose of levothyroxine (12.5–25 μg/day) which is slowly up titrated every 4–6 weeks in increments of 12.5–25 μg/day until euthyroidism is achieved. |
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