PedAM
Pediatric Disease Annotations & Medicines
| Disease | hypothyroidism |
| Phenotype | C0028754|obesity |
| Sentences | 11 |
| PubMedID- 23051081 | hypothyroidism was associated with obesity and perturbations in lipid profile particularly increase in total cholesterol, c-ldl, apob, apob/apoa1 and lp(a) and decrease in apoa1 and c-hdl. |
| PubMedID- 23956749 | The resulting anovulation and thin endometrial lining may potentially be protective over time and balance the obesity often associated with hypothyroidism [16]. |
| PubMedID- 23351558 | Our exclusion criteria were defined as: heavy smokers (more than twenty cigarettes per day); alcohol consumption; pregnancy; recent surgery, patients with coronary heart disease; known cases of diabetes mellitus; patients with proven malignancy, asthma, chronic cough, chronic inflammatory disease and psychological problems; history of chronic kidney and liver disease, obesity due to endocrine disease (hypothyroidism or uncontrolled thyroid disease); and genetic obesity syndrome. |
| PubMedID- 26511212 | Untreated or sub-clinical hypothyroidism is associated with insulin resistance, obesity, adverse effects on cardiovascular system, hypertension and in turn risk of nephropathy. |
| PubMedID- 23564558 | Osas frequency is likely to increase in hypothyroidism because of obesity, macroglossia, dysfunctional upper respiratory tractus (urt) musculature, deposition of mucopolysaccharides in urt tissues, and decreased ventilatory control. |
| PubMedID- 26004610 | Objective: obesity has been associated with hypothyroidism and cardiac autonomic dysfunction. |
| PubMedID- 24872812 | Several studies have suggested a role for obesity in the development of thyroid insufficiency in the tissue based on reduced expression of t3 and tsh receptors in the fat of obese subjects [25]. |
| PubMedID- 24971238 | Subjects < 30 or > 60 years of age and pregnant women, and those with chronic renal failure, infection, inflammation, diabetes mellitus type 2, hyperlipidemia, thyroid function disorders, secondary obesity (due to hypothyroidism or cushing syndrome), and some chronic illnesses were excluded. |
| PubMedID- 24971248 | Exclusion criteria were; subjects under 18 or over 30 years old, bmi (less than 18.5 kg/m2, between 25 and 29.9 kg/m2 or equal or more than 40 kg/m2), pregnant women, acute and chronic renal failure, hypertension, cerebrovascular accidents (cva), ischemic heart disease (ihd), opiate users, cigarette smokers and alcoholics, infections, inflammations, diabetes mellitus type two, hyperlipidemia, thyroid function disorders, secondary obesity (due to hypothyroidism or cushing syndrome), dietary treatment for cardiovascular risk factors, weight loss in the previous two months, and some chronic illnesses. |
| PubMedID- 24251274 | [3031] however, obesity in hypothyroidism is not primarily due to excess adiposity as increase in bodyweight in thyroid deficiency state is mostly due to accumulation of water and mucopolysaccharides in subcutaneous tissues. |
| PubMedID- 21335378 | Although patients and lay individuals almost immediately associate hypothyroidism with obesity, the incidence of hypothyroidism in obese individuals is not increased, and changes in body composition during the transition from severe hypothyroidism to mild thyrotoxicosis are meager (9–11). |
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