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PedAM

Pediatric Disease Annotations & Medicines




Disease hypothyroidism
Phenotype C0002892|pernicious anemia
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PubMedID- 22876245 Additional clinical features are less common, and include diabetes type i, hypothyroidism, atrophic gastritis with or without pernicious anemia (biermer’s disease), cutaneous manifestations (alopecia areata, vitiligo, transient skin rash during fever episodes, non-infectious nail dysplasia), ocular symptoms (keratoconjunctivitis, dry eye, iridocyclitis, cataract, retinal detachment, and optic atrophy; merenmies and tarkkanen, 2000), enamel dysplasia, hyposplenism/asplenia (implying vaccination against streptococcus pneumonia,haemophilus influenzae, and hepatitis b as well as antibiotic prophylaxis), autoimmune hepatitis, tubulo-interstitial nephritis, or organized pneumonitis.
PubMedID- 20409541 [primary autoimmune hypothyroidism in patients with pernicious anemia].

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