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PedAM

Pediatric Disease Annotations & Medicines




Disease hypogonadism
Phenotype C0948265|metabolic syndrome
Sentences 5
PubMedID- 20938417 Effects of metformin and short-term lifestyle modification on the improvement of male hypogonadism associated with metabolic syndrome.
PubMedID- 20835560 Caldas et al.11 described the relationship between insulin and hypogonadism in men with metabolic syndrome and concluded that hypogonadism was associated with insulin resistance and may be a marker of metabolic abnormalities.
PubMedID- 22313648 Male partial hypogonadotrophic hypogonadism with gynaecomastia and metabolic syndrome.
PubMedID- 22469460 The significant inverse association between il-6 and t suggests an important role of low-grade visceral fat inflammation in the central hypogonadism associated with the metabolic syndrome.
PubMedID- 22031847 Furthermore, the beneficial effects of gtx-024 on insulin sensitivity and triglycerides, known associations of hypogonadism with metabolic syndrome and cardiovascular risk [33–35], as well as the low cardiovascular risk observed in randomized clinical trials of testosterone supplementation [18], suggest that the overall cardiovascular risk/benefit ratio for gtx-024 is low.

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