PedAM
Pediatric Disease Annotations & Medicines
| Disease | hypogonadism |
| Phenotype | C0021359|infertile |
| Sentences | 4 |
| PubMedID- 23762577 | Humans and mice with loss-of-function mutations of the genes encoding kisspeptins (kiss1) or kisspeptin receptor (kiss1r) are infertile due to hypogonadotropic hypogonadism [151, 152]. |
| PubMedID- 20518947 | A karyotype should be considered in a young teenager or infertile man with primary hypogonadism to diagnose klinefelter syndrome (2–4). |
| PubMedID- 23741292 | Female irs2 null mice develop moderate obesity and are infertile due to hypogonadism [1], [36]. |
| PubMedID- 24396593 | Thus, although spontaneous fertility can occur, the majority of females with btm is infertile due to hypogonadotropic hypogonadism (hh) and need assisted reproductive techniques. |
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