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PedAM

Pediatric Disease Annotations & Medicines




Disease hypoglycemia
Phenotype C0020456|hyperglycemia
Sentences 21
PubMedID- 23806096 This study confirms our previous results that recovering hypoglycemia with hyperglycemia worsens endothelial function and inflammation, being oxidative stress generation the possible cause of this effect [10].
PubMedID- 22701841 Alcohol is implicated in fasting hyperglycemia, potentiation of drug-induced hypoglycemia or reactive hypoglycemia, hypoglycemia unawareness, synergistic effect on neuropathy and retinopathy, interaction with antidiabetic agents (lactic acidosis with metformin, disulfiram like reaction with chlorpropamide, hepatopathy leading to reduction in dose).
PubMedID- 21838054 In the treatment of type 2 diabetes aimed at prevention of cardiovascular events impacting the prognosis of affected patients, it is critically important not only to lower hbalc values but to find a way to improve postprandial hyperglycemia without causing hypoglycemia thus minimizing drastic glycemic variations or to maintain favorable glycemic control with daily glycemic variations in mind.
PubMedID- 21402737 Conclusion: when over-riding iit cdss recommendations, nurses overwhelmingly administered ltr doses, which emphasized prevention of hypoglycemia but interfered with hyperglycemia control, especially when bg was >150 mg/dl.
PubMedID- 22986916 Results: continuous glucose monitoring before treatment showed asymptomatic hypoglycemia with postprandial hyperglycemia (2.5 g/l, 13.75 mmol/l).
PubMedID- 21731863 As these drugs target hyperglycemia independently of insulin, risk of hypoglycemia should be negligible.
PubMedID- 20071562 However, there is no change in the order of perfusion of different islet endocrine cell types in hypoglycemia compared with hyperglycemia, with the islet core of beta-cells usually perfused first.
PubMedID- 21437084 Metformin monotherapy is a highly appropriate first-line pharmaceutical intervention as it reduces hyperglycemia without concomitant hypoglycemia or weight gain – side effects that are problematic with hypoglycemic agents.
PubMedID- 22675341 Due to this properties, the hormone reduces hyperglycemia without inducing hypoglycemia in patients with type 2 diabetes [3].
PubMedID- 22336443 One candidate is glycemic variability, which must be differentiated from postprandial hyperglycemia since hypoglycemia can also result in inflammatory activation.
PubMedID- 25317246 Treatment of type 1 diabetes mellitus has always posed a challenge to balance hyperglycemia control with hypoglycemia episodes.
PubMedID- 22145468 Both cases presented typical clinical features of hepatomegaly, hypophosphatemic rickets, severely stunted growth, fasting hypoglycemia along with postprandial hyperglycemia, and proximal renal tubular dysfunction with disproportionately severe glucosuria.
PubMedID- 23214078 Thus, dpp-4 inhibitor can improve postprandial hyperglycemia, without causing hypoglycemia in patients with diabetes.
PubMedID- 20929995 Several factors may explain the observed reduction in cvd events and hospitalization in exenatide versus non–exenatide-treated patients: greater reduction of hyperglycemia with less hypoglycemia and/or improvement in cvd risk factors, including weight, lipids, and blood pressure (14).
PubMedID- 25281044 While hypoglycemia can lead to organ dysfunction, hyperglycemia can lead to surgical site infections (ssi).
PubMedID- 24679123 The continuous need for antidiabetic drugs in dm treatment and chronic hyperglycemia lead to infections, ketoacidosis, hypoglycemia, and micro- and macrovascular disorders affecting the retina and nervous, renal, cardiovascular, and cerebrovascular systems[13].
PubMedID- PMC3363597 Since hypoglycemia can lead to organ dysfunction, hyperglycemia seems to boost surgical site infections (ssi) [1].
PubMedID- 26177629 They tested the pharmacodynamics of these constructs in fasted dogs and demonstrated that they could prevent hypoglycemia without inducing temporary hyperglycemia, an event often associated with glucagon alone.
PubMedID- 24594704 Our studies showed that hypoglycemia following hyperglycemia in ferrets produces increases in glucagon and pancreatic polypeptide, similar to that observed in human studies [41].
PubMedID- 22374642 Given the alterations in the time-action profiles observed in our study, we speculate that postdinner hyperglycemia and increased risk of nocturnal hypoglycemia in the study by nguyen et al.
PubMedID- 23594397 Whereas hyperglycemia was the target of the interventional trials, hypoglycemia was their unifying complication.

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