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PedAM

Pediatric Disease Annotations & Medicines




Disease hyperuricemia
Phenotype C0020459|hyperinsulinemia
Sentences 3
PubMedID- 26064845 hyperuricemia has attributed to hyperinsulinemia in metabolic syndrome and decreased excretion of uric acid causing endothelial dysfunction in kidney leads to renal disease and cardiovascular disorders.
PubMedID- 20920653 Because hyperuricemia in hyperinsulinemia is primarily due to impaired renal ua excretion, its association with incident hf would suggest a direct ua effect.
PubMedID- 23588856 hyperuricemia has been attributed to hyperinsulinemia in metabolic syndrome and to decreased uric acid excretion in kidney dysfunction, and is not acknowledged as a main mediator of metabolic syndrome, renal disease, and cardiovascular disorder development.

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