PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperuricemia |
| Phenotype | C0011881|diabetic nephropathy |
| Sentences | 1 |
| PubMedID- 22701621 | In this study, we used streptozotocin (stz)-induced diabetic nephropathy model with hyperuricemia and dyslipidemia in rats, and found over-expression of renal inflammasome components nlrp3, apoptosis-associated speck-like protein and caspase-1, resulting in elevation of il-1β and il-18, with subsequently deteriorated renal injury. |
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