PedAM
Pediatric Disease Annotations & Medicines
| Disease | hypersplenism |
| Phenotype | C0040034|thrombocytopenia |
| Sentences | 23 |
| PubMedID- 26267788 | In addition, it has been reported that splenomegaly leads to thrombocytopenia, associated with hypersplenism, in more than 60% of patients with hs schistosomiasis, especially in the advanced stages of the disease; however, relatively few patients present symptoms due to hypersplenism and need surgery [10]. |
| PubMedID- 23275773 | Other chemotherapeutic agents, including 5-fluorodeoxyuridine and irinotecan have also been associated with thrombocytopenia due to hypersplenism but to a much lesser degree than oxaliplatin [4, 8, 13]. |
| PubMedID- 25788181 | Background/purpose: thrombocytopenia due to hypersplenism precludes percutaneous liver biopsy in many cases of chronic liver disease (cld). |
| PubMedID- 23132324 | The indications for surgery were pain and discomfort caused by a large spleen (5-15 cm below the costal margin) and symptomatic hypersplenism with leucopenia, thrombocytopenia, and anemia. |
| PubMedID- 22057175 | A splenectomy was done due to persistent thrombocytopenia associated with hypersplenism, with good response of the platelets counts. |
| PubMedID- 25879015 | However, sorafenib cannot be used in patients with severe thrombocytopenia, one of the complications of hypersplenism, owing to its platelet-decreasing effect. |
| PubMedID- 23833091 | Severe thrombocytopenia due to hypersplenism treated with partial splenic embolisation. |
| PubMedID- 24019767 | Its common symptoms include hepatosplenomegaly, thrombocytopenia due to hypersplenism and bone manifestations. |
| PubMedID- 21734807 | Aim: to study the safety and feasibility of total embolization of the main splenic artery as a supplemental treatment modality for hypersplenism with thrombocytopenia or leukocytopenia accompanying liver cirrhosis. |
| PubMedID- 23055649 | [13] other causes of non-immune thrombocytopenia in association with tuberculosis include hypersplenism,[4] intravascular coagulation,[5] thrombotic thrombocytopenic purpura[6] and hemophagocytic syndrome. |
| PubMedID- 23781362 | The major problem faced was hypersplenism leading to thrombocytopenia and anemia. |
| PubMedID- 20796158 | Background and aim: thrombocytopenia due to hypersplenism is usually a serious condition in cirrhotic patients who have undergone invasive procedures. |
| PubMedID- 23901200 | hypersplenism may lead to thrombocytopenia, who may present with bleeding similar to our case. |
| PubMedID- 20467465 | Primary indications for psss were repeated variceal bleeding despite endoscopic therapy (6), symptomatic hypersplenism with thrombocytopenia (2), and liver dysfunction in the setting of hepatic vein thrombosis (2). |
| PubMedID- 22708981 | Peripheral platelet destruction or sequestration is the major mechanism for thrombocytopenia, with hypersplenism being an important cause. |
| PubMedID- 25737395 | thrombocytopenia due to hypersplenism in oncological disease: partial splenic embolization during palliative treatment. |
| PubMedID- 22287875 | hypersplenism as a cause of thrombocytopenia may reflect portal hypertension from cirrhosis, collagen vascular disease, or rarely primary neoplasm of the spleen. |
| PubMedID- 23420139 | While in some patients the disease remained static, in a larger proportion a more severe disease developed characterized by portal hypertension, the latter leading to hypersplenism with neutropenia and thrombocytopenia and, in some cases, to ascites. |
| PubMedID- 22588242 | The theory of portal decompression to improve thrombocytopenia due to hypersplenism has led to the study of transjugular intrahepatic portosystemic shunt (tips) as a potential therapy. |
| PubMedID- 22985446 | Introduction: hypersplenism with thrombocytopenia is a common complication of cirrhosis with portal hypertension. |
| PubMedID- 24255616 | Lower values ofplatelet counts are seen especially in patients with hs after gastrointestinal bleeding.this was also seen in the current work with the possible cause being the increase ofspleen and hypersplenism leading to frequent thrombocytopenia, leukopenia and anemia. |
| PubMedID- 22771590 | Severe thrombocytopenia due to hypersplenism is a rare complication in sarcoidosis23 which was seen in one patient. |
| PubMedID- 25233685 | Indications for surgery were pain and abdominal discomfort caused by spleen enlargement, as well as symptomatic hypersplenism with leucopenia, thrombocytopenia and anemia. |
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