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PedAM

Pediatric Disease Annotations & Medicines




Disease hyperphosphatemia
Phenotype C0020502|hyperparathyroidism
Sentences 6
PubMedID- 22702634 Prolonged parathyroid gland exposure to hyperphosphatemia leads to secondary hyperparathyroidism characterized by hyperplasia of the glands and excessive secretion of parathyroid hormone (pth), which causes renal osteodystrophy.
PubMedID- 25861621 Thirdly, while in patients with chronic kidney disease parathyroidectomy is indicated in case of severe hyperparathyroidism associated with hypercalcemia and/or hyperphosphatemia that cannot be efficiently controlled by medical therapy [28], there are no recommendations available for transplant patients with persistent hypercalcemic hyperparathyroidism.
PubMedID- 22629024 hyperparathyroidism along with hyperphosphatemia and increased calcium phosphate ion product are identified as independent cvd risk factors.
PubMedID- 26554928 In the case of ckd, additional hyperphosphatemia (complicated by secondary hyperparathyroidism and uremic toxins) has been described as an independent risk factor for the development of mvc [3].
PubMedID- 22593665 In addition, phosphate retention and renal secondary hyperparathyroidism are common complications of ckd [2–7], and hyperphosphatemia is associated with the development of renal lesions in dogs and cats [2–7].
PubMedID- 21349164 Inadequately treated hyperphosphatemia in crf leads to secondary hyperparathyroidism and extraosseous calcification of soft tissues [5,6].

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