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PedAM

Pediatric Disease Annotations & Medicines




Disease hyperparathyroidism
Phenotype C0151468|thyroid adenoma
Sentences 22
PubMedID- 24932128 An unusual case of brown tumor of hyperparathyroidism associated with ectopic parathyroid adenoma.
PubMedID- 26462047 Unlike solitary parathyroid adenoma, parathyroid hyperplasia in patients with secondary hyperparathyroidism hitherto is difficult to assess with any imaging modality.
PubMedID- 22576020 Accumulation of non-phosphorylated active beta-catenin has been reported to commonly occur in parathyroid adenomas from patients with primary hyperparathyroidism (phpt), either due to the aberrantly spliced internally truncated wnt receptor lrp5 (lrp5delta) or to a stabilizing mutation of beta-catenin.
PubMedID- 26395176 Mutations of this protein lead to autosomal dominant hyperparathyroidism-jaw tumor syndrome with parathyroid adenoma or carcinoma, mandibular or maxillary fibro-osseous tumors, and renal neoplastic and non-neoplastic abnormalities such as wilms’ tumor, hamartoma, or cystic renal disease [11-13].
PubMedID- 21512735 She was diagnosed with primary hyperparathyroidism because of parathyroid adenoma and treated with surgery where a synchronous thyroid papillary carcinoma was detected.
PubMedID- 22142470 For several years, the calcimimetic cinacalcet (sensipar or mimpara) has been used for the treatment of primary hyperparathyroidism (phpt), hypercalcemia associated with parathyroid adenomas [5,6], parathyroid hyperplasia due to kidney disease [7] and parathyroid cancer [8].
PubMedID- 21178047 Objective: the objective of our study was to evaluate the accuracy of dynamic contrast-enhanced 4d mdct in the preoperative identification of parathyroid adenomas in patients with primary hyperparathyroidism (phpt) and a history of failed surgery or unsuccessful localization on standard imaging.
PubMedID- 26191410 She was also found to have primary hyperparathyroidism with bilateral inferior parathyroid adenoma.
PubMedID- 25202755 We present a case report of an ectopic mediastinal parathyroid adenoma leading to primary hyperparathyroidism and responsible for a persistent asymptomatic hypercalcemia.
PubMedID- 23484975 Preoperative localisation of parathyroid adenomas in patients with persistent hyperparathyroidism relies currently on a combination of ultrasonography, technetium sestamibi scintigraphy/single photon emission computed tomography (spect), magnetic resonance imaging and venous sampling of parathyroid hormone.
PubMedID- 22698932 Persistent hyperparathyroidism owing to a giant parathyroid adenoma in posterior mediastinum.
PubMedID- 21747852 Hpt-jt is an autosomal dominant syndrome of primary hyperparathyroidism with parathyroid adenomas (with or without carcinomas), mandibular or maxillary fibro-osseous tumors, and renal tumours.
PubMedID- 25574767 Further investigations then revealed the presence of a solitary parathyroid adenoma with coexistent hyperparathyroidism which was then managed surgically.
PubMedID- 26024849 Objectives: to identify frequent mri features of parathyroid adenomas (ptas) in patients with primary hyperparathyroidism (phpt) using a fast protocol with a 3 t magnet.
PubMedID- 25427653 Aim: to investigate the efficacy of pet/ct with 11c-methionine for localizing parathyroid adenomas in patients with suspected primary hyperparathyroidism and inconclusive results of cervical ultrasonography and 99mtc-mibi-spect/ct.
PubMedID- 23482497 Serum calcium, serum parathyroid hormone, and weight of parathyroid adenomas in patients with primary hyperparathyroidism results by ultrasonographic localization.
PubMedID- 20338394 Aim: to evaluate the accuracy of ultrasound and parathyroid scintigraphy using single photon-emission computed tomography/computed tomography (spect/ct) for the preoperative localization of solitary parathyroid adenomas in patients with primary hyperparathyroidism who would be suitable for minimally invasive parathyroid surgery.
PubMedID- 22322895 The aim of the present study was to evaluate the diagnostic accuracy and imaging patterns of colour doppler ultrasonography (us) and compare it with grayscale us, 99m-tc methoxyisobutylisonitrile (mibi) scans, and combined us and mibi scans in the preoperative diagnosis of parathyroid adenomas in patients with primary hyperparathyroidism (phpt).
PubMedID- 22310246 Conclusions: dual-phase (99m)tc sestamibi scintigraphy with spect/ct enables to identify a parathyroid adenoma in about two-thirds of patients with primary hyperparathyroidism and allows the surgeon to plan appropriate surgery.
PubMedID- 23493928 Primary hyperparathyroidism (phpt) typically results from solitary parathyroid adenoma (80% of cases) and occurs in 0.1–0.35 percent of population [1–3].
PubMedID- 23198183 Spontaneous resolution of primary hyperparathyroidism in parathyroid adenoma.
PubMedID- 23759694 Purpose: to compare the accuracy of preoperative parathyroid adenoma localization in patients with primary hyperparathyroidism (phpt) due to a single adenoma using a detailed 4-quadrant analysis and to identify patient and tumor characteristics associated with accurate preoperative localization.

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