PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperparathyroidism |
| Phenotype | C0020437|hypercalcemia |
| Sentences | 50 |
| PubMedID- 23146463 | Background: cinacalcet is an effective treatment for hypercalcemia due to persistent hyperparathyroidism (hpt) in patients who have undergone kidney transplantation (kt). |
| PubMedID- 24251162 | Acute pancreatitis due to hypercalcemia associated with hyperparathyroidism (hpt) is not very common. |
| PubMedID- 24251127 | We describe a case of hyperparathyroidism with concomitant hypercalcemia accompanied by central pontine myelinosis without hyponatremia/hyperosmolality or associated rapid corrections of sodium, which developed as a consequence of severe hypokalaemia. |
| PubMedID- 26442164 | We report a 60-year-old female patient manifesting hypercalcemia due to hyperparathyroidism, a solitary fibrous tumor (sft) of the pleura, multiple gastrointestinal stromal tumors (gists), and moyamoya disease associated with nf1. |
| PubMedID- 25641446 | hypercalcemia with hyperparathyroidism (hpt) was present in 5 patients and hyperuricemia in 3. |
| PubMedID- 23146456 | Persistent hyperparathyroidism associated with hypercalcemia and hyperphosphatemia have been associated with poor graft and patient survivals. |
| PubMedID- 25926120 | The presence of isolated primary hyperparathyroidism, as a cause of hypercalcemia in cancer patients, has been described in approximately 5-10% of the patients. |
| PubMedID- 21151209 | Diagnosis: severe persistent hyperparathyroidism associated with mild hypercalcemia following renal transplantation. |
| PubMedID- 26019872 | A de novo heterozygous inactivating mutation of calcium-sensing receptor (casr) gene typically causes neonatal hyperparathyroidism (nhpt) with moderate hypercalcemia and hyperparathyroid bone disease. |
| PubMedID- 25505684 | hypercalcemia associated with lithium-induced hyperparathyroidism (lih) is a common, but easily overlooked, complication of lithium treatment. |
| PubMedID- 24251163 | On follow-up she is diagnosed to have primary hyperparathyroidism with hypercalcemia due to left inferior parathyroid adenoma which improved with intravenous (iv) zolindronic acid therapy and now she is planned to undergo parathyroidectomy. |
| PubMedID- 20510722 | hypercalcemia associated with primary hyperparathyroidism has frequently resulted in the development of pancreatitis and peptic ulcer disease; however, the pathophysiologic mechanism of this association remains uncertain. |
| PubMedID- 22840059 | Today, primary hyperparathyroidism usually presents with mild hypercalcemia (within 1 mg/dl above the upper limit of normal), is usually asymptomatic, and diagnosed incidentally on routine investigations for minor non-specific complains. |
| PubMedID- 25741940 | Antenatal bartter syndrome presenting as hyperparathyroidism with hypercalcemia and hypercalciuria: a case report and review. |
| PubMedID- 24241361 | Post-transplant hypercalcemia due to persistent secondary hyperparathyroidism (hpt) has a high prevalence in the first 3 months after surgery and decreases during the first year, but it persists over time in around 5-10% of renal transplant patients. |
| PubMedID- 20191460 | It has long been thought that parathyroidectomy was the only way to solve the problem of stabilized hypercalcemia associated with moderate-severe persistent hyperparathyroidism after kidney transplant. |
| PubMedID- 23112902 | hypercalcemia due to primary hyperparathyroidism, and familial hypocalciuric hypercalcemia (fhh) should be considered as differential diagnosis. |
| PubMedID- 25861621 | hypercalcemia associated with hyperparathyroidism is a common complication after kidney transplantation [1]. |
| PubMedID- 21394466 | Elevated pth values may also persist in some patients and hypercalcemia, in combination with hyperparathyroidism, has been traditionally considered a sign of autonomous pth secretion and an indication for parathyroidectomy in transplant recipients [16, 17]. |
| PubMedID- 23026597 | Conclusions: cinacalcet is an effective alternative for the treatment of hypercalcemia in patients with persistent hyperparathyroidism after kt. |
| PubMedID- 23799171 | Because the serology and imaging tests were only suggestive of hypercalcemia due to hyperparathyroidism, the patient was referred to the ent department where the diagnosis of primary hyperparathyroidism with osteitis fibrosa cystica due to a parathyroid tumor was considered. |
| PubMedID- 24959180 | Cinacalcet (sensipar), a calcimimetic drug, is available for the treatment of secondary hyperparathyroidism associated with renal failure, hypercalcemia in parathyroid cancer, and the treatment of severe hypercalcemia in patients with primary hyperparathyroidism unable to undergo parathyroidectomy [17–19]. |
| PubMedID- 23330456 | Cinacalcet is also expected to be useful in the treatment of intractable hypercalcemia in patients with primary hyperparathyroidism for whom parathyroidectomy is indicated but surgery is clinically inappropriate or contraindicated. |
| PubMedID- 21112866 | Although the safety and efficacy of this drug in treating hypercalcemia associated with hyperparathyroidism have not yet been established in clinically controlled trials, its off-label use is not uncommon. |
| PubMedID- 22431942 | Functional parathyroid cyst: a rare cause of malignant hypercalcemia with primary hyperparathyroidism-a case report and review of the literature. |
| PubMedID- 24334568 | Metastatic calcification occurs in the setting of hypercalcemia, most commonly attributable to hyperparathyroidism, often secondary to renal dysfunction. |
| PubMedID- 23198183 | On july 21, 2012 a 71-year-old caucasian woman with primary hyperparathyroidism awaiting surgery because of significant hypercalcemia and hypercalciuria presented to her local emergency department after acute onset of discomfort within her neck that ran transversely from left to right from the mid to lower neck, sore throat, and difficulty swallowing that had progressively gotten worse over the previous 3 days. |
| PubMedID- 24072092 | Maternal hypercalcemia due to unrecognized hyperparathyroidism suppresses parathyroid activity in the fetus, resulting in impaired parathyroid responsiveness to hypocalcemia after birth (1,2,3,4). |
| PubMedID- 20145928 | If left untreated, hyperparathyroidism can lead to symptoms of hypercalcemia, renal complications, and bone disease connected to hyperparathyroidism, which is characterized by high turnover and remodeling rates leading to osteoporosis and increased fracture risk. |
| PubMedID- 22577545 | In addition to the previous mechanism, several other factors like uremic toxins, increased circulating endogenous nos inhibitors like asymmetric dimethylarginine, secondary hyperparathyroidism leading to hypercalcemia, and increased expression of endothelin a receptors have also been implicated in the pathogenesis of hypertension in ckd. |
| PubMedID- 24033403 | Background: after renal transplantation (rtx), hypercalcemia, mainly due to persistent hyperparathyroidism, and hypophosphatemia, caused by the improved ability to excrete phosphorus in the renal tubules, are expected. |
| PubMedID- 21286893 | A case of acute pancreatitis as a first symptom of primary hyperparathyroidism with severe hypercalcemia is reported. |
| PubMedID- 26239247 | Those with elevated pth level were assumed to have pth-mediated hypercalcemia (the majority of which had primary hyperparathyroidism or php). |
| PubMedID- 22620673 | In the neonatal period, homozygous inactivating mutations result in neonatal severe hyperparathyroidism (nshpt) with severe symptomatic hypercalcemia, undermineralized bones, rib cage deformity, and long-bone and rib fractures [3]. |
| PubMedID- 26240800 | Fifth, it is important to determine if there is a family history of gastrinoma, zollinger-ellison syndrome (zes), or type i multiple endocrine neoplasia; their secondary symptoms, including chronic diarrhea or hypercalcemia due to hyperparathyroidism, should be investigated for acid hypersecretion. |
| PubMedID- 25817305 | Biochemical tests for malignancy and metabolic disease were negative for all patients except patient 8. initial investigations during her admission had shown normocalcemia, but she was found to have hypercalcemia with possible hyperparathyroidism 1 year after fixation of her peri-implant fracture. |
| PubMedID- 24302625 | Thus, adult male and female crh−120/+ mice, aged 8–12 weeks, were hypercalcemic (table 1), and this was associated with significantly reduced plasma pth concentrations (table 1), indicating that the hypercalcemia was not due to hyperparathyroidism associated with parathyroid tumors. |
| PubMedID- 21660912 | Hypocalcemia, frequently seen in the setting of chronic renal insufficiency, results in prolonged st segment and qt interval while hypercalcemia, usually seen with hyperparathyroidism, results in shortening of both intervals. |
| PubMedID- 23225300 | Introduction: hyperparathyroidism often presents with asymptomatic hypercalcemia or minimal, unspecific symptoms and the middle-age female is the predominant population. |
| PubMedID- 24736147 | A 28 year-old girl admitted for a bone tumor of the knee, the blood test shows hypercalcemia with hyperparathyroidism, bone biopsy revealed giant cell lesions characteristic of brown tumors. |
| PubMedID- 21078161 | Parathyroid carcinoma (pc) is a rare cause of primary hyperparathyroidism with characteristic marked hypercalcemia and highly elevated parathyroid hormone levels. |
| PubMedID- 23232684 | A very rare type of primary hyperparathyroidism with severe hypercalcemia in an infant. |
| PubMedID- 22876055 | Patients with secondary or tertiary hyperparathyroidism, or other causes of hypercalcemia such as malignancy, vitamin d intoxication, immobilization, medications, hyperthyroidism, and other endocrine diseases, were excluded. |
| PubMedID- 21887663 | Based on laboratory tests and ultrasound imaging, acute pancreatitis with hypercalcemia due to tertiary hyperparathyroidism was diagnosed. |
| PubMedID- 25755881 | More than 90% of cases of hypercalcemia are due to primary hyperparathyroidism or malignancy. |
| PubMedID- 20582171 | [10–1157–60] metastatic pulmonary calcification has also been reported in a patient with hypercalcemia due to hyperparathyroidism who recovered from pneumonia with sepsis and whose hrct images demonstrated localized parenchymal airspace calcification that was limited to the lower lobes[61] [figure 26]. |
| PubMedID- 21391355 | [primary hyperparathyroidism as a cause of hypercalcemia in a patient with breast cancer]. |
| PubMedID- 23581265 | In infancy, hypercalcemia generally occurs due to hyperparathyroidism, familial hypocalciuric hypercalcemia, subcutaneous fat necrosis, total parenteral nutrition administration, hyperthyroidism, and adrenal insufficiency. |
| PubMedID- 23202713 | When diagnosing anterior mediastinal tumor with hypercalcemia, atypical carcinoid of thymus with hyperparathyroidism should be considered. |
| PubMedID- 24736693 | Great majority of patients with severe hypercalcemia is attributable to either primary hyperparathyroidism or malignancy. |
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