PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperparathyroidism |
| Phenotype | C0001430|adenoma |
| Sentences | 14 |
| PubMedID- 25709494 | To our surprise, the pathologist report did not support parathyroid adenoma as a cause of hyperparathyroidism, but of diffuse parathyroid hyperplasia (figure 6), which is only cited in 10%–15% of patients with primary hyperparathyroidism.13 the distinction between primary and secondary disease by histology seems to be very difficult, although nuclear pleomorphism favors a primary origin, while gland nodularity favors a secondary cause.14 a case somewhat similar to ours featuring a parathyroid adenoma and secondary hyperparathyroidism in stage iii ckd has been published recently by brucculeri and haydon,15 with beneficial results noted for cinacalcet after parathyroidectomy. |
| PubMedID- 23230541 | In fact, the sensitivity of 99tc-sestamibi parthyroid scintigraphy for detecting and localizing a single adenoma in patients with primary hyperparathyroidism ranges from 54 to 96%,[254035–44] while the specificity, calculated only in a few studies, ranges from 83 to 99%. |
| PubMedID- 26462047 | Unlike solitary parathyroid adenoma, parathyroid hyperplasia in patients with secondary hyperparathyroidism hitherto is difficult to assess with any imaging modality. |
| PubMedID- 25574767 | Further investigations then revealed the presence of a solitary parathyroid adenoma with coexistent hyperparathyroidism which was then managed surgically. |
| PubMedID- 24426402 | Correlation of biochemical markers of primary hyperparathyroidism with single adenoma weight and volume. |
| PubMedID- 24426429 | After accurate preoperative localisation of the adenoma in patients with primary hyperparathyroidism, mip with iopth measurement offers a safe and successful outcome. |
| PubMedID- 24716007 | Primary hyperparathyroidism with an adenoma or hyperplasia producing hypercalcemia is a relatively common endocrine problem that is treated surgically. |
| PubMedID- 23493928 | Primary hyperparathyroidism (phpt) typically results from solitary parathyroid adenoma (80% of cases) and occurs in 0.1–0.35 percent of population [1–3]. |
| PubMedID- 22218874 | Methods: fifty-nine primary hyperparathyroidism patients with a single adenoma underwent curative surgery. |
| PubMedID- 26395176 | Mutations of this protein lead to autosomal dominant hyperparathyroidism-jaw tumor syndrome with parathyroid adenoma or carcinoma, mandibular or maxillary fibro-osseous tumors, and renal neoplastic and non-neoplastic abnormalities such as wilms’ tumor, hamartoma, or cystic renal disease [11-13]. |
| PubMedID- 23759694 | Purpose: to compare the accuracy of preoperative parathyroid adenoma localization in patients with primary hyperparathyroidism (phpt) due to a single adenoma using a detailed 4-quadrant analysis and to identify patient and tumor characteristics associated with accurate preoperative localization. |
| PubMedID- 25202755 | We present a case report of an ectopic mediastinal parathyroid adenoma leading to primary hyperparathyroidism and responsible for a persistent asymptomatic hypercalcemia. |
| PubMedID- 21512735 | She was diagnosed with primary hyperparathyroidism because of parathyroid adenoma and treated with surgery where a synchronous thyroid papillary carcinoma was detected. |
| PubMedID- 22310246 | Conclusions: dual-phase (99m)tc sestamibi scintigraphy with spect/ct enables to identify a parathyroid adenoma in about two-thirds of patients with primary hyperparathyroidism and allows the surgeon to plan appropriate surgery. |
Page: 1