PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperhomocysteinemia |
| Phenotype | C0042373|vascular disease |
| Sentences | 18 |
| PubMedID- 25194809 | Background and aims: hyperhomocysteinemia (hhcy) is associated with cardiovascular diseases and is thought to induce endogenous oxidative stress and causes many cellular damages. |
| PubMedID- 20091801 | Perturbations of homocysteine metabolism, particularly intracellular and subsequently circulating accumulation of homocysteine (i.e., hyperhomocysteinemia), are associated with vascular disease risk, as well as other pathologies. |
| PubMedID- 22573925 | Thus, we see that in indians, vascular disease due to hyperhomocysteinemia is correlated to the serum folate and vitamin b12 concentrations. |
| PubMedID- 20980407 | Folic acid supplementation is regarded as a promising approach for prevention and treatment of cardiovascular disease associated with hyperhomocysteinemia due to its hcy-lowering effect. |
| PubMedID- 19267198 | Background: homocysteine levels in circulation are determined by several factors and hyperhomocysteinemia is reportedly associated with cardiovascular diseases and dementia. |
| PubMedID- 25822522 | hyperhomocysteinemia, which is associated with vascular diseases [24,25], birth defects such as spina bifida [26], and neurodegenerative diseases such as alzheimer’s disease [27]. |
| PubMedID- 24847701 | Hyperglycemia, dyslipidemia and hyperhomocysteinemia are associated with both adult cardiovascular disease (cvd) and having a child with a congenital heart disease (chd). |
| PubMedID- 22886392 | High levels of homocysteine (hcy), known as hyperhomocysteinemia (hhcy), are associated with cerebrovascular diseases, such as vascular dementia, stroke, and alzheimer's disease. |
| PubMedID- 22520390 | Conclusion: the present study confirms high hyperhomocysteinemia prevalence in patients with extracranial cerebrovascular disease, although no relationship between plaque complication phenomena and this cardiovascular risk factor was observed. |
| PubMedID- 23912038 | High levels of homocysteine (hcy), known as hyperhomocysteinemia are associated with neurovascular diseases. |
| PubMedID- 23936148 | hyperhomocysteinemia has been associated with cardiovascular disease in several prospective studies [18] and numerous explanatory pathomechanisms have been proposed [19-21]. |
| PubMedID- 24783194 | hyperhomocysteinemia is strongly associated with cardiovascular diseases. |
| PubMedID- 23569455 | Many clinical and epidemiological studies published during the last three decades have shown that even mild hyperhomocysteinemia is associated with vascular disease [6,8,9,10]. |
| PubMedID- 24386282 | In other studies, fa acid supplementation has been reported to improve endothelial dysfunction in hyperhomocysteinemia (hhcy) patients with vascular disease [41], [42] including asymptomatic hhcy subjects [43], [44]. |
| PubMedID- 20227264 | hyperhomocysteinemia is associated with cerebro- and cardiovascular disease in industrialized countries, mostly resulting from protein rich diet and sedentary life style. |
| PubMedID- 19913585 | An elevated level of homocysteine (hcy), known as hyperhomocysteinemia (hhcy), was associated with neurovascular diseases. |
| PubMedID- 23791689 | Objective: hyperhomocysteinemia is associated with an elevated cardiovascular disease risk. |
| PubMedID- 24231341 | hyperhomocysteinemia (hhcy) is associated with cardiovascular disease, atherosclerosis and reactive oxygen species generation. |
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