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PedAM

Pediatric Disease Annotations & Medicines




Disease hyperglycemia
Phenotype C0086543|cataract
Sentences 4
PubMedID- 20806076 While the onset of cataract due to hyperglycemia was observed in diabetic animals after four weeks of stz injection and progressed to mature cataract by eight weeks in untreated diabetic lenses, feeding of ginger delayed both onset and progression of cataract in diabetic rats in a dose dependent manner (figure 1a).
PubMedID- 24391466 Two weeks after diabetic modeling by stz injection, cataract was developed due to hyperglycemia in approximately 92% of lenses in diabetic rats.
PubMedID- 24155984 While the onset of cataract due to hyperglycemia was observed in diabetic animals after four weeks of stz injection and progressed to mature cataract by eight weeks in untreated diabetic group, feeding of dietary curcumin delayed both onset and progression of cataract (β= -0.379; se=0.080) as compared to untreated group (figure 2) and this is consistent with our previous observations [12].
PubMedID- 22355255 However, different mechanisms are involved in the development of cataract due to hyperglycemia [5].

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