PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Phenotype | C0085207|maternal diabetes |
| Sentences | 2 |
| PubMedID- 25756053 | We conclude that hyperglycemia, which results from maternal diabetes and precedes embryo implantation, deregulates the intrauterine developmental timeline, restricts embryo-fetal growth, and primarily delays the remodeling and maturation of the structures derived from neural crest cells. |
| PubMedID- 22805998 | Using this model of maternal diabetes, with hyperglycemia moderated by twice daily insulin, we previously described significantly enhanced aortic contractility and endothelial dysfunction in female but not male offspring 17. we therefore sought to extend studies in this model to determine whether offspring exposed to short-term (7-day) maternal hyperglycemia in utero would display sex-specific increased blood pressure. |
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