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PedAM

Pediatric Disease Annotations & Medicines




Disease hyperglycemia
Phenotype C0042373|vascular disease
Sentences 9
PubMedID- 20409333 The meta-analysis conducted by selvin and colleagues [7] reviewed 13 prospective cohort studies, and the pooled results indicated that chronic hyperglycemia was associated with cardiovascular disease in patients with t2dm.
PubMedID- 24381557 Chronic hyperglycemia is associated with vascular disease and neurotoxicity leading to neuronal damage (tomlinson and gardiner, 2008).
PubMedID- 21124220 Purpose of review: hyperglycemia is frequent in patients with cerebrovascular disease.
PubMedID- 26266268 In this regard, the effect of nonclinical microvascular disease due to chronic hyperglycemia might be playing a role as a potential determinant [34].
PubMedID- 21453785 Although the mechanisms by which insulin-resistance and hyperglycemia lead to cardiovascular disease are still incompletely understood, all mechanisms apparently converge on the vessel wall and the endothelium as a common disease target.
PubMedID- 23564922 The role of hyperglycemia favoring cardiovascular disease in type 1 diabetes seems to be relevant; however, many other classical and less classical risk factors also seem to be involved (7).
PubMedID- 22275081 Thus, there is considerable interest in factors that link overnutrition, insulin resistance, and hyperglycemia with vascular disease.
PubMedID- 21270199 Diabetes is characterized by hyperglycemia and associated with increased cardiovascular disease (cvd) risk (1).
PubMedID- 26089898 Chronic hyperglycemia leads to vascular disease, and multiple studies in patients and animal models and in vitro have revealed that hyperglycemia alters endothelial metabolism and function, causing vascular injury.

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