PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Phenotype | C0035309|retinopathy |
| Sentences | 8 |
| PubMedID- 22346115 | The traditional risk factors for diabetic retinopathy include duration of diabetes, hyperglycemia, hypertension, and dyslipidemia, which explains only some degree of variance in the risk of diabetic retinopathy.39 studies have shown the association of multiple systemic inflammatory factors in the progression of diabetic retinopathy, and a further analysis of diabetic vitreous samples has provided insights into novel proinflammatory markers in the process.4041 these novel inflammatory risk factors identified in the human population not only serve as potential biomarkers, but they also give insights into the development of potential molecular targets for treating diabetic retinopathy. |
| PubMedID- 23671858 | It was reported that the association of hyperglycemia with retinopathy is stronger than that with nephropathy [3]. |
| PubMedID- 23745545 | The major risk factors for diabetic retinopathy include duration of diabetes, hyperglycemia, and hypertension, but this is accountable for only a small amount of the variation in the risk of diabetic retinopathy. |
| PubMedID- 23448719 | Objective: diabetic retinopathy (dr) is associated with hyperglycemia-driven microvascular pathology and neuronal compromise in the retina. |
| PubMedID- 20302881 | Increased microvascular permeability contributes to the development of diabetic retinopathy and is associated with hyperglycemia and accumulation of advanced glycation end products (ages). |
| PubMedID- 21916837 | Diabetic retinopathy is associated with hyperglycemia, and there is convincing evidence that oxidative stress (the overproduction of reactive oxygen species (ros)) measured indirectly in patients, is related to the severity of diabetic complications. |
| PubMedID- 22272370 | The diabetic retinopathy cascade begins with chronic hyperglycemia affecting the normal progression of glycolysis. |
| PubMedID- 24672252 | It has been estimated that 366 million people worldwide will develop type 2 diabetes by 2030.1 chronic hyperglycemia leads to microvascular (retinopathy, neuropathy, renal failure) and macrovascular (ischemic heart and cerebrovascular disease, lower limb ischemia) complications. |
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