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PedAM

Pediatric Disease Annotations & Medicines




Disease hyperglycemia
Phenotype C0022658|nephropathy
Sentences 7
PubMedID- 23716916 Reduction of weight in obese type 2 diabetes mellitus (t2dm) individuals is emerging as a significant strategy in the reduction of proteinuria in diabetic nephropathy along with control of hyperglycemia, hypertension, and dyslipidemia.
PubMedID- 24432038 hyperglycemia may lead to nephropathy by a number of mechanisms, including hypertrophy and thickening of the basement membrane, increased endothelial cell permeability to albumin, and increased matrix protein synthesis [3,4].
PubMedID- 24319552 [1] in diabetic individuals, long-standing hyperglycemia leads to nephropathy, neuropathy, and cardiovascular diseases.
PubMedID- 24960275 There are various pathological renal remodeling processes leading to diabetic nephropathy because of the chronic hyperglycemia during diabetes mellitus.
PubMedID- 23646149 hyperglycemia leads to nephropathy by various mechanisms, such as increased endothelial cell permeability to albumin, hypertrophy and thickening of the basement membrane.
PubMedID- 23441190 It is also well known that only about one-third of the diabetic patients develop nephropathy due to hyperglycemia [1].
PubMedID- 24843474 Microangiopathy, such as retinopathy and nephropathy, is correlated with long‐term chronic hyperglycemia.2 in contrast, patients with impaired glucose tolerance (igt), a stage just before the diagnosis of diabetes, particularly those with postprandial hyperglycemia, have a higher risk of developing macrovascular events, such as acute coronary syndrome.

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