PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Phenotype | C0022116|ischemia |
| Sentences | 5 |
| PubMedID- 20636251 | Based on promising data on pbn in hyperglycemic-ischemic injury (9) and the compelling feasibility of sulfonated nitrones in the treatment of ischemic brain damage, we hypothesized s-pbn to be neuroprotective in focal ischemia-reperfusion with concomitant hyperglycemia in rats. |
| PubMedID- 21904663 | The results of our study elucidate the role of hyperglycemia in ischemia reperfusion injury during renal transplantation and have clinical implications for the perioperative management of glucose levels. |
| PubMedID- 26301160 | hyperglycemia interacts with ischemia in a synergistic way on wound repair and myofibroblast differentiation. |
| PubMedID- 23091615 | We propose that ischemia-reperfusion together with hyperglycemia trigger greater oxidative stress that may result in increased misfolded proteins that are targeted for removal by ups degradation. |
| PubMedID- 25660722 | Incorporating long-term degradation of blood supply from the retinal capillaries into the model yields insight into the effects of progressive ischemia associated with prolonged hyperglycemia, suggesting time-scales over which therapeutic mitigation could have beneficial effect. |
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