PedAM
Pediatric Disease Annotations & Medicines
| Disease | hyperglycemia |
| Phenotype | C0020598|hypoglycemia |
| Sentences | 22 |
| PubMedID- 22675341 | Due to this properties, the hormone reduces hyperglycemia without inducing hypoglycemia in patients with type 2 diabetes [3]. |
| PubMedID- 22336443 | One candidate is glycemic variability, which must be differentiated from postprandial hyperglycemia since hypoglycemia can also result in inflammatory activation. |
| PubMedID- 23806096 | The aim of this study is to explore if glp-1 can protect endothelial function and can reduce inflammation when hypoglycemia is recovered with hyperglycemia, and if this protective action is related to a decrease in oxidative stress. |
| PubMedID- 23882057 | First, hypoglycemia is a result of treatment of hyperglycemia by oral insulin secretagogues or insulin. |
| PubMedID- 21402737 | Conclusion: when over-riding iit cdss recommendations, nurses overwhelmingly administered ltr doses, which emphasized prevention of hypoglycemia but interfered with hyperglycemia control, especially when bg was >150 mg/dl. |
| PubMedID- 26273677 | Recurrent hypoglycemia, presence of symptomatic hyperglycemia, diabetic ketosis (dk), diabetic ketoacidosis (dka), and nonketotic hyperosmolar syndrome (nkhs) were considered metabolic complications. |
| PubMedID- 22145468 | Both cases presented typical clinical features of hepatomegaly, hypophosphatemic rickets, severely stunted growth, fasting hypoglycemia along with postprandial hyperglycemia, and proximal renal tubular dysfunction with disproportionately severe glucosuria. |
| PubMedID- 21437084 | Metformin monotherapy is a highly appropriate first-line pharmaceutical intervention as it reduces hyperglycemia without concomitant hypoglycemia or weight gain – side effects that are problematic with hypoglycemic agents. |
| PubMedID- 20929995 | Several factors may explain the observed reduction in cvd events and hospitalization in exenatide versus non–exenatide-treated patients: greater reduction of hyperglycemia with less hypoglycemia and/or improvement in cvd risk factors, including weight, lipids, and blood pressure (14). |
| PubMedID- 20071562 | However, there is no change in the order of perfusion of different islet endocrine cell types in hypoglycemia compared with hyperglycemia, with the islet core of beta-cells usually perfused first. |
| PubMedID- 23214078 | Thus, dpp-4 inhibitor can improve postprandial hyperglycemia, without causing hypoglycemia in patients with diabetes. |
| PubMedID- 23842097 | Injecting appropriate doses of insulin based on blood glucose concentration is important; failure to do so may lead to hypoglycemia (due to overdosage) and hyperglycemia (due to underdosage). |
| PubMedID- 25281044 | While hypoglycemia can lead to organ dysfunction, hyperglycemia can lead to surgical site infections (ssi). |
| PubMedID- 21838054 | In the treatment of type 2 diabetes aimed at prevention of cardiovascular events impacting the prognosis of affected patients, it is critically important not only to lower hbalc values but to find a way to improve postprandial hyperglycemia without causing hypoglycemia thus minimizing drastic glycemic variations or to maintain favorable glycemic control with daily glycemic variations in mind. |
| PubMedID- 25317246 | Treatment of type 1 diabetes mellitus has always posed a challenge to balance hyperglycemia control with hypoglycemia episodes. |
| PubMedID- 22986916 | Results: continuous glucose monitoring before treatment showed asymptomatic hypoglycemia with postprandial hyperglycemia (2.5 g/l, 13.75 mmol/l). |
| PubMedID- 26177629 | They tested the pharmacodynamics of these constructs in fasted dogs and demonstrated that they could prevent hypoglycemia without inducing temporary hyperglycemia, an event often associated with glucagon alone. |
| PubMedID- 24679123 | The continuous need for antidiabetic drugs in dm treatment and chronic hyperglycemia lead to infections, ketoacidosis, hypoglycemia, and micro- and macrovascular disorders affecting the retina and nervous, renal, cardiovascular, and cerebrovascular systems[13]. |
| PubMedID- 24594704 | Our studies showed that hypoglycemia following hyperglycemia in ferrets produces increases in glucagon and pancreatic polypeptide, similar to that observed in human studies [41]. |
| PubMedID- 26146634 | Actually, gip acts as a hormone that stabilizes glucose in t2dm by increasing glucagon response during hypoglycemia, the secretion rate of insulin during hyperglycemia, and both mechanisms when fasting glucose levels are around 8 mmol/l [8]. |
| PubMedID- PMC3363597 | Since hypoglycemia can lead to organ dysfunction, hyperglycemia seems to boost surgical site infections (ssi) [1]. |
| PubMedID- 23209068 | The underlying pathophysiologies that link diabetes and development of ad are, recurrent hypoglycemia, antioxidative stress due to hyperglycemia, atherosclerosis and vascular lesions, and abnormal insulin signaling in the brain. |
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