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PedAM

Pediatric Disease Annotations & Medicines




Disease hyperglycemia
Phenotype C0011884|diabetic retinopathy
Sentences 7
PubMedID- 22346115 The traditional risk factors for diabetic retinopathy include duration of diabetes, hyperglycemia, hypertension, and dyslipidemia, which explains only some degree of variance in the risk of diabetic retinopathy.39 studies have shown the association of multiple systemic inflammatory factors in the progression of diabetic retinopathy, and a further analysis of diabetic vitreous samples has provided insights into novel proinflammatory markers in the process.4041 these novel inflammatory risk factors identified in the human population not only serve as potential biomarkers, but they also give insights into the development of potential molecular targets for treating diabetic retinopathy.
PubMedID- 20873150 The pupillary dilatation test in the dark and 2.5% irifrin and 1% mydriacyl tests revealed a reduction in the papillary dilatation amplitude in hyperglycemia in patients with diabetic retinopathy.
PubMedID- 23448719 Objective: diabetic retinopathy (dr) is associated with hyperglycemia-driven microvascular pathology and neuronal compromise in the retina.
PubMedID- 21916837 diabetic retinopathy is associated with hyperglycemia, and there is convincing evidence that oxidative stress (the overproduction of reactive oxygen species (ros)) measured indirectly in patients, is related to the severity of diabetic complications.
PubMedID- 20302881 Increased microvascular permeability contributes to the development of diabetic retinopathy and is associated with hyperglycemia and accumulation of advanced glycation end products (ages).
PubMedID- 22891217 Although numerous observations have underscored the association of hyperglycemia with inflammation in diabetic retinopathy, the pathogenic mechanism leading to chronic retinal inflammation in diabetes is unclear.
PubMedID- 23745545 The major risk factors for diabetic retinopathy include duration of diabetes, hyperglycemia, and hypertension, but this is accountable for only a small amount of the variation in the risk of diabetic retinopathy.

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