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PedAM

Pediatric Disease Annotations & Medicines




Disease hypercalcemia
Phenotype C0020503|secondary hyperparathyroidism
Sentences 2
PubMedID- 24959180 Cinacalcet (sensipar), a calcimimetic drug, is available for the treatment of secondary hyperparathyroidism associated with renal failure, hypercalcemia in parathyroid cancer, and the treatment of severe hypercalcemia in patients with primary hyperparathyroidism unable to undergo parathyroidectomy [17–19].
PubMedID- 22577545 In addition to the previous mechanism, several other factors like uremic toxins, increased circulating endogenous nos inhibitors like asymmetric dimethylarginine, secondary hyperparathyroidism leading to hypercalcemia, and increased expression of endothelin a receptors have also been implicated in the pathogenesis of hypertension in ckd.

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