Home Contact Sitemap

PedAM

Pediatric Disease Annotations & Medicines




Disease hypercalcemia
Phenotype C0020502|hyperparathyroidism
Sentences 44
PubMedID- 23225300 Introduction: hyperparathyroidism often presents with asymptomatic hypercalcemia or minimal, unspecific symptoms and the middle-age female is the predominant population.
PubMedID- 23146456 Persistent hyperparathyroidism associated with hypercalcemia and hyperphosphatemia have been associated with poor graft and patient survivals.
PubMedID- 25926120 The presence of isolated primary hyperparathyroidism, as a cause of hypercalcemia in cancer patients, has been described in approximately 5-10% of the patients.
PubMedID- 21286893 A case of acute pancreatitis as a first symptom of primary hyperparathyroidism with severe hypercalcemia is reported.
PubMedID- 24736693 Great majority of patients with severe hypercalcemia is attributable to either primary hyperparathyroidism or malignancy.
PubMedID- 21234416 Most patients with primary hyperparathyroidism are diagnosed because of routine findings of hypercalcemia [69, table  1-2].
PubMedID- 24736147 A 28 year-old girl admitted for a bone tumor of the knee, the blood test shows hypercalcemia with hyperparathyroidism, bone biopsy revealed giant cell lesions characteristic of brown tumors.
PubMedID- 20510722 hypercalcemia associated with primary hyperparathyroidism has frequently resulted in the development of pancreatitis and peptic ulcer disease; however, the pathophysiologic mechanism of this association remains uncertain.
PubMedID- 20145928 If left untreated, hyperparathyroidism can lead to symptoms of hypercalcemia, renal complications, and bone disease connected to hyperparathyroidism, which is characterized by high turnover and remodeling rates leading to osteoporosis and increased fracture risk.
PubMedID- 20191460 It has long been thought that parathyroidectomy was the only way to solve the problem of stabilized hypercalcemia associated with moderate-severe persistent hyperparathyroidism after kidney transplant.
PubMedID- 26251716 Administration of ketoconazole has been successfully used for the treatment of hypercalcaemia associated with hyperparathyroidism and sarcoidosis.
PubMedID- 23026597 Conclusions: cinacalcet is an effective alternative for the treatment of hypercalcemia in patients with persistent hyperparathyroidism after kt.
PubMedID- 25949433 hyperparathyroidism with hypercalcaemia in chronic kidney disease: primary or tertiary?
PubMedID- 25641446 hypercalcemia with hyperparathyroidism (hpt) was present in 5 patients and hyperuricemia in 3.
PubMedID- 23330456 Cinacalcet is also expected to be useful in the treatment of intractable hypercalcemia in patients with primary hyperparathyroidism for whom parathyroidectomy is indicated but surgery is clinically inappropriate or contraindicated.
PubMedID- 21112866 Although the safety and efficacy of this drug in treating hypercalcemia associated with hyperparathyroidism have not yet been established in clinically controlled trials, its off-label use is not uncommon.
PubMedID- 23198183 A 71 yo woman with primary hyperparathyroidism awaiting surgery because of significant hypercalcemia and hypercalciuria presented to the local emergency department with the chief complaints of discomfort in her neck, sore throat, and difficulty swallowing.
PubMedID- 23199021 In 1996 a total parathyroidectomy with autotransplantation into the right brachioradial muscle was performed for severe hyperparathyroidism with a pth of 820 pg/ml, hypercalcemia and hyperphosphatemia.
PubMedID- 25861621 hypercalcemia associated with hyperparathyroidism is a common complication after kidney transplantation [1].
PubMedID- 22577545 In addition to the previous mechanism, several other factors like uremic toxins, increased circulating endogenous nos inhibitors like asymmetric dimethylarginine, secondary hyperparathyroidism leading to hypercalcemia, and increased expression of endothelin a receptors have also been implicated in the pathogenesis of hypertension in ckd.
PubMedID- 22431942 Functional parathyroid cyst: a rare cause of malignant hypercalcemia with primary hyperparathyroidism-a case report and review of the literature.
PubMedID- 21391355 [primary hyperparathyroidism as a cause of hypercalcemia in a patient with breast cancer].
PubMedID- 23764372 In patients with primary hyperparathyroidism, the state of hyperparathyroid hypercalcemia is associated with reduced muscle strength and impaired quality of life (qol).
PubMedID- 24251162 Acute pancreatitis due to hypercalcemia associated with hyperparathyroidism (hpt) is not very common.
PubMedID- 21151209 Diagnosis: severe persistent hyperparathyroidism associated with mild hypercalcemia following renal transplantation.
PubMedID- 25505684 hypercalcemia associated with lithium-induced hyperparathyroidism (lih) is a common, but easily overlooked, complication of lithium treatment.
PubMedID- 24334568 Metastatic calcification occurs in the setting of hypercalcemia, most commonly attributable to hyperparathyroidism, often secondary to renal dysfunction.
PubMedID- 24959180 Cinacalcet (sensipar), a calcimimetic drug, is available for the treatment of secondary hyperparathyroidism associated with renal failure, hypercalcemia in parathyroid cancer, and the treatment of severe hypercalcemia in patients with primary hyperparathyroidism unable to undergo parathyroidectomy [17–19].
PubMedID- 21394466 Elevated pth values may also persist in some patients and hypercalcemia, in combination with hyperparathyroidism, has been traditionally considered a sign of autonomous pth secretion and an indication for parathyroidectomy in transplant recipients [16, 17].
PubMedID- 25817305 Biochemical tests for malignancy and metabolic disease were negative for all patients except patient 8. initial investigations during her admission had shown normocalcemia, but she was found to have hypercalcemia with possible hyperparathyroidism 1 year after fixation of her peri-implant fracture.
PubMedID- 24251127 We describe a case of hyperparathyroidism with concomitant hypercalcemia accompanied by central pontine myelinosis without hyponatremia/hyperosmolality or associated rapid corrections of sodium, which developed as a consequence of severe hypokalaemia.
PubMedID- 24251163 On follow-up she is diagnosed to have primary hyperparathyroidism with hypercalcemia due to left inferior parathyroid adenoma which improved with intravenous (iv) zolindronic acid therapy and now she is planned to undergo parathyroidectomy.
PubMedID- 25741940 Antenatal bartter syndrome presenting as hyperparathyroidism with hypercalcemia and hypercalciuria: a case report and review.
PubMedID- 21078161 Parathyroid carcinoma (pc) is a rare cause of primary hyperparathyroidism with characteristic marked hypercalcemia and highly elevated parathyroid hormone levels.
PubMedID- 22271812 Background: hypercalcaemia resulting from primary hyperparathyroidism (phpt) can cause a wide range of symptoms, including cognitive disorders, psychiatric symptoms and muscle weakness.
PubMedID- 23081733 Primary hyperparathyroidism in a patient with familial hypocalciuric hypercalcaemia due to a novel mutation in the calcium-sensing receptor gene.
PubMedID- 21660912 Hypocalcemia, frequently seen in the setting of chronic renal insufficiency, results in prolonged st segment and qt interval while hypercalcemia, usually seen with hyperparathyroidism, results in shortening of both intervals.
PubMedID- 26019872 Infants that are heterozygous for casr mutations may present neonatal hyperparathyroidism (nhpt) with moderate hypercalcemia and a marked elevation of pth levels, which leads to apparent hyperparathyroid bone disease (1)(2)(3).
PubMedID- 23228121 Objective: to report the italian experience on cinacalcet use following its approval by the european medical agency (ema) to control hypercalcaemia in patients with primary hyperparathyroidism (phpt).
PubMedID- 22840059 Today, primary hyperparathyroidism usually presents with mild hypercalcemia (within 1 mg/dl above the upper limit of normal), is usually asymptomatic, and diagnosed incidentally on routine investigations for minor non-specific complains.
PubMedID- 22876055 Patients with secondary or tertiary hyperparathyroidism, or other causes of hypercalcemia such as malignancy, vitamin d intoxication, immobilization, medications, hyperthyroidism, and other endocrine diseases, were excluded.
PubMedID- 21879659 In primary hyperparathyroidism, repercussions of pronounced hypercalcemia on organs and systems are of essential importance.
PubMedID- 23232684 A very rare type of primary hyperparathyroidism with severe hypercalcemia in an infant.
PubMedID- 22620673 In the neonatal period, homozygous inactivating mutations result in neonatal severe hyperparathyroidism (nshpt) with severe symptomatic hypercalcemia, undermineralized bones, rib cage deformity, and long-bone and rib fractures [3].

Page: 1