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PedAM

Pediatric Disease Annotations & Medicines




Disease hiv infections
Phenotype C0024312|lymphopenia
Sentences 3
PubMedID- 21209878 In line with this model, cd4+ t-lymphopenia in the course of hiv disease is characterized by a substantial increase in il-7 plasma levels, and yet such an il-7-enriched milieu fails to preserve the peripheral t-cell pool.
PubMedID- 26344343 Phase i/ii trials in hiv infected subjects with persistent lymphopenia have demonstrated that the administration of il-7 was able to restore circulating cd4 t-cell counts as well as the frequency of cd8+ t cells, mainly those with a central memory (tcm) phenotype [91] without any effect on the number of regulatory t cells.
PubMedID- 21810564 We conclude that tuberculosis may be associated with cd4 and cd8 lymphopenia even in patients without human immunodeficiency virus infection, there was the tendency of recovery towards normality especially of the cd4 and cd8 counts after treatment, and that disseminated disease is associated specifically with profound cd4 lymphopenia.

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