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PedAM

Pediatric Disease Annotations & Medicines




Disease hepatitis a
Phenotype C0018799|heart disease
Sentences 2
PubMedID- 22585408 Exclusion criteria included significant liver, renal, or heart disease; evidence of hepatitis as indicated by a threefold increase in of two out of three liver enzymes; diabetes mellitus or other untreated endocrine disease; recent (within 3 months) treatment with anabolic steroids; alcohol or drug abuse; ongoing anticoagulant therapy; androgen-secreting tumors of the ovary and adrenal or any ovarian tumor (e.g., sertoli-leydig); polycystic ovary syndrome (pcos); and/or hyperthecosis, nonclassical adrenal hyperplasia, cushing's syndrome, glucocorticoid resistance, pregnancy, hyperprolactinoma, hypothyroidism, lactose intolerance, or any other circumstance deemed exclusionary by the pi or study physician.
PubMedID- 20525274 They could not be hospitalized (unless discharge was expected within 10 days); be receiving chronic oxygen therapy or any ventilatory support; have significant congenital heart disease; have evidence of infection with hepatitis a, b, or c virus or hiv; have any acute illness, including acute rsv infection; known renal impairment, hepatic dysfunction, chronic seizure disorder, or immunodeficiency; have suspected serious allergic or immune-mediated events in association with prior receipt of immunoglobulins, blood products, or other foreign proteins; have received within the past 120 days or currently be receiving immunoglobulin products, palivizumab, or any investigational agent.

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