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PedAM

Pediatric Disease Annotations & Medicines




Disease hepatitis
Phenotype C0042769|viral infection
Sentences 36
PubMedID- 20663176 There are many known types of liver insult ranging from viral infection (due to hepatitis b, c and d), autoimmunity (primary biliary cirrhosis, autoimmune hepatitis), inherited diseases (cystic fibrosis, hereditary haemachromotosis), dietary (non-alcoholic fatty liver disease) or chemical (alcohol) causes, and parasitic infection, the details of which are beyond the scope of this article but have been summarised by wallace et al [6].
PubMedID- 23146476 The most common etiology was toxic exposure (no cases were related to acetaminophen overdose), followed by viral infection (all because of acute hepatitis b).
PubMedID- 25182146 Cirrhosis due to metabolic syndrome, alcohol consumption, viral infection with hepatitis c virus (hcv) is also involved in its development.
PubMedID- 21790072 Viral hepatitis associated with adenoviral infection has been reported in california sea lions zalophus californianus admitted to rehabilitation centers along the california coast since the 1970s.
PubMedID- 23808468 Context: the common risk factors for hepatocellular carcinoma (hcc) include persistent viral infection with either hepatitis b or c virus, alcohol abuse, hemochromatosis, and metabolic syndrome.
PubMedID- 20617863 Background: the efficacy of combination therapy with peginterferon plus ribavirin to eradicate viral infection in patients with chronic hepatitis c (chc) is well established; moreover, it is able to arrest or even reverse liver fibrosis.
PubMedID- 23725349 A number of factors such as viral infections (hepatitis b and c), alcoholism, autoimmune diseases and nonalcoholic fatty liver disease etc., may cause liver fibrosis [1], which corresponds to an increased production of extracellular matrix components(collagens in particular) and leads to liver dysfunction and cirrhosis [2,3].
PubMedID- 21062497 Globally, the predominant cause of hcc is viral infection with hepatitis b virus (hbv) or hepatitis c virus (hcv) [4].
PubMedID- 24824502 Finally, ampk may be involved in viral infection: downregulation of ampk during hepatitis c virus infection appears to be essential for efficient viral replication.
PubMedID- 26576450 A review of 64 cases of patients who experienced severe viral infections with hepatitis b, cytomegalovirus infection, and varicella-zoster virus after rituximab treatment demonstrated that the median time period from start of rituximab to diagnosis of viral infection was 5 months (range: 1–20 months); our cases fell within this range [6].
PubMedID- 24313162 The major risk factors for developing hcc are viral infection (i.e., with the hepatitis b or c viruses), chronic alcoholism, and exposure to toxic substances called aflatoxins.
PubMedID- 24213234 Hepatocellular carcinoma (hcc) is a problem worldwide, especially in asian countries [1,2,3] unlike most solid cancers, the incidence and mortality rates for hcc are projected to increase substantially in many countries over the next 20 years, mostly as a result of viral infections with hepatitis c and hepatitis b [4].
PubMedID- 20820946 The vast majority of cases are a consequence of a preexisting chronic viral infection due to either hepatitis b with or without associated hepatitis d or hepatitis c [7–9].
PubMedID- 24260365 The viral infection leads to chronic hepatitis in the majority of patients (>80%) and often progresses to cirrhosis or hepatocellular carcinoma [1], [2].
PubMedID- 20823335 We employed this clustering feature to define knockdowns which harm viral infection efficiency of human hepatitis c virus.
PubMedID- 23548687 viral infection with hepatitis c and hepatitis b was present in 13.7 and 3.6% of patients, respectively.
PubMedID- 24478542 viral infection with hepatitis c virus (hcv) has a high propensity in becoming chronic and it is the major cause of hepatocellular carcinoma (hcc) worldwide.
PubMedID- 25885972 [49] other serious concerns are related to active viral infections with hepatitis b and c viruses, which besides causing liver dysfunction are potentially dangerous to anesthesia providers.
PubMedID- 25888777 While adenoviral infection of sea lions causes hepatitis and death [13,14], the dolphins infected with putative tursiops adenovirus 1 suffered self-limiting disease, with no signs of hepatitis.
PubMedID- 26514735 Liver stiffness performed best in predicting severe fibrosis in patients with chronic viral infection, correctly identifying 78.7% of chronic hepatitis b and 88.6% of chronic hepatitis c subjects.
PubMedID- 24339718 Evaluation for evidence of viral infection with either hepatitis b or c was negative.
PubMedID- 26347518 Background/aims: the immunoregulatory molecules programmed death 1 (pd-1) and cytotoxic t lymphocyte-associated antigen 4 (ctla-4) are associated with the dysfunction of antiviral effector t-cells, which leads to t-cell exhaustion and persistent viral infection in patients with chronic hepatitis c and chronic hepatitis b.
PubMedID- 22606519 The other conditions prevalent in tropical countries like acute viral infections leading to hepatitis, enteric fever and leptospirosis should be figured in the differential diagnosis.
PubMedID- 23855159 hepatitis resulting from viral infection is common worldwide and is associated with significant morbidity and mortality.
PubMedID- 26300931 Persistent viral infections with either hepatitis b virus (hbv) or hepatitis c virus (hcv) are believed to be closely related to developing hcc, accounting for 53% and 25% of all hcc cases, respectively (4).
PubMedID- 20580843 States during which cytokine systems are activated (e.g., during viral infection or during treatment of chronic hepatitis c and various malignancies with ifn alpha, etc.) can be associated with depression-like syndromes or even full-blown depressive episodes.
PubMedID- 23271667 In addition to its high frequency of metastasis, hepatocellular carcinoma recurrence is characterized by multicentric carcinogenesis arising in the liver damaged by viral infection with the hepatitis b or hepatitis c virus.
PubMedID- 25960817 viral infection with hepatitis b virus (hbv), hepatitis c virus (hcv), and cytomegalovirus (cmv) was excluded, and an acute epstein-barr virus (ebv) infection was serologically confirmed (immunoglobulin m (igm) – 168 au/ml, immunoglobulin g (igg) – 21.4 au/ml).
PubMedID- 25596475 Chronic viral infection, such as infection of chronic hepatitis b, hepatitis c and hiv, has increased levels of interleukin 10 in peripheral blood.
PubMedID- 24877058 The integration of hbv dna into hepatocytes is an integral step for persistent viral infection that leads to chronic hepatitis b infection, which ultimately causes hcc [164].
PubMedID- 22419004 Most patients with hcc have an underlying liver disease caused by either chronic viral infection due to hepatitis b or hepatitis c virus or non-viral etiologic risk factors such as alcohol, fatty liver disease, dietary aflatoxin exposure, smoking and diabetes mellitus.
PubMedID- 23907631 In african or asian countries hcc has become the most common cause for cancer-related death, mainly as a consequence of viral infections with hepatitis b and c-viruses (hbv; hcv).
PubMedID- 22192700 Other viral infection, especially with hepatitis c, can be associated with necrotizing pns vasculitis [32].
PubMedID- 23426905 Chronic viral infection with the hepatitis b virus (hbv) or hepatitis c virus (hcv) appears to be the most significant causes of hcc (4).
PubMedID- 24376853 There is evidence that viral infections (hepatitis c, hiv and influenza) are associated with an increased production of ros and that could be involved in the pathogenesis [33,34].
PubMedID- 23446427 No patient had evidence of viral infection (hepatitis b, c and hiv were negative in all cases), and all had normal “basic” immunological testing (complement, antinuclear factors, ena, ana, immunoglobulin levels).

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