PedAM
Pediatric Disease Annotations & Medicines
| Disease | hemolytic anemia |
| Phenotype | C0027947|neutropenia |
| Sentences | 1 |
| PubMedID- 21772952 | Evans syndrome (es) is an autoimmune disorder characterized by thrombocytopenia and/or neutropenia associated with hemolytic anemia (aha).1–3 it is a potentially life-threatening condition that may be associated with other underlying autoimmune or lymph-proliferative disorders.4 standard treatment consists of transfusions, corticosteroids and immunoglobulins (ivig); second-line treatment in es evolved over the last decade, and includes at present anti-cd20 rituximab, vincristine, alkalizing agents, mycophenolate mofetil (mmf) or cyclosporine (cya).5–6,8–14 long-term remissions induced by splenectomy are less frequent than in uncomplicated immune thrombocytopenia purpura (itp). |
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