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PedAM

Pediatric Disease Annotations & Medicines




Disease hemolytic anemia
Phenotype C0023530|leukopenia
Sentences 3
PubMedID- 23301216 Clinical indications for a blood smear review request by a physician include (a) unexplained anemia, thrombocytopenia and/or leukopenia, (b) suspicion of microangiopathic hemolytic anemia (e.g., thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, etc), hemoglobinopathy (e.g., ss, sc, cc, etc.
PubMedID- 24864270 This ongoing registry had recruited 2170 chinese sle patients who fulfilled the sle classification criteria revised by the american college of rheumatology (acr) in 1997 [9] during the period between april 2009 and february 2010. patients were required to fulfill at least 4 of the following 11 criteria: (1) malar rash; (2) discoid rash; (3) photosensitivity; (4) oral or nasopharyngeal ulceration; (5) nonerosive arthritis involving 2 or more peripheral joints; (6) pleuritis or pericarditis; (7) nephropathy: persistent proteinuria > 0.5 grams per day or cellular casts; (8) neurologic involvement: seizures or psychosis in the absence of offending drugs or known metabolic derangements; (9) hematologic involvement: hemolytic anemia with reticulocytosis or leukopenia (<4,000/mm3 on ≥2 occasions) or lymphopenia (<1,500/mm3 on ≥2 occasions) or thrombocytopenia (<100,000/mm3) in the absence of offending drugs; (10) immunologic disorder: antibody to native double-stranded dna in abnormal titer or presence of antibody to sm nuclear antigen or positive finding of antiphospholipid antibodies; (11) positive antinuclear antibody.
PubMedID- 26063969 hemolytic anemia with reticulocytosis or leukopenia <4.000/mm3 on ≥2 occasions or lymphopenia <1.500/mm3 on ≥2 occasions or thrombocytopenia <100.000/mm3 in the absence of offending drugs.

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