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PedAM

Pediatric Disease Annotations & Medicines




Disease hemolytic anemia
Phenotype C0019048|hemoglobinuria
Sentences 3
PubMedID- 26043387 Paroxysmal nocturnal hemoglobinuria is manifests with a chronic hemolytic anemia from uncontrolled complement activation, a propensity for thrombosis and marrow failure.
PubMedID- 22851928 In the present, replacement therapy of c1-inhibitor is also another established treatment for hereditary angioedema in addition to anti-c5 antibodies for c-dependent hemolytic anemia in patients with paroxysmal nocturnal hemoglobinuria, respectively [155,156].
PubMedID- 25914813 Paroxysmal nocturnal hemoglobinuria presents with hemolytic anemia, although it is also associated with thrombosis and pancytopenia.

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